Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | CRHR1 | P34998 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3984821 | 0.98 | ALDH1A1 (0.47) | ALDH1A1TP53ELANECRHR1TDP1 | |
| SCHEMBL21065741 | 0.96 | ALDH1A1 (0.46) | ALDH1A1TP53ELANECRHR1TDP1 | |
| SCHEMBL25276708 | 0.94 | ALDH1A1 (0.45) | ALDH1A1TP53ELANECRHR1TDP1 | |
| SCHEMBL25276932 | 0.94 | ALDH1A1 (0.53) | ALDH1A1TP53ELANECRHR1TDP1 | |
| SCHEMBL25270443 | 0.92 | ALDH1A1 (0.55) | ALDH1A1TP53ELANECRHR1TDP1 | |
| SCHEMBL25223165 | 0.92 | ALDH1A1 (0.55) | ALDH1A1TP53ELANECRHR1TDP1 | |
| SCHEMBL25223117 | 0.92 | ALDH1A1 (0.55) | ALDH1A1TP53ELANECRHR1TDP1 | |
| SCHEMBL25276793 | 0.92 | ALDH1A1 (0.55) | ALDH1A1TP53ELANECRHR1TDP1 | |
| SCHEMBL25278338 | 0.92 | ALDH1A1 (0.55) | ALDH1A1TP53ELANECRHR1TDP1 | |
| SCHEMBL25224584 | 0.92 | ALDH1A1 (0.54) | ALDH1A1TP53ELANECRHR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10766972-B2 | Modified conjugated diene-based polymer and method for producing the same, and modified conjugated diene-based polymer composition | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2020-09-08 | — | — | US | disclosed |
| EP-3260476-B1 | MODIFIED CONJUGATED DIENE-BASED POLYMER, MANUFACTURING METHOD THEREOF, AND MODIFIED CONJUGATED DIENE-BASED POLYMER COMPOSITION | ASAHI CHEMICAL IND (JP) | 2019-05-08 | — | — | EP | disclosed |
| US-20180037674-A1 | Modified Conjugated Diene-Based Polymer and Method for Producing the Same, and Modified Conjugated Diene-Based Polymer Composition | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2018-02-08 | — | — | US | disclosed |
| EP-3260476-A1 | MODIFIED CONJUGATED DIENE-BASED POLYMER, MANUFACTURING METHOD THEREOF, AND MODIFIED CONJUGATED DIENE-BASED POLYMER COMPOSITION | Asahi Kasei Kabushiki Kaisha (JP) | 2017-12-27 | — | — | EP | disclosed |