Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.78 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8267885 | 1.00 | GAA (0.78) | GAAUSP2POLBTSHRMEN1 | |
| SCHEMBL28689598 | 0.89 | GAA (0.62) | GAAUSP2POLBTSHRMEN1 | |
| SCHEMBL22748852 | 0.89 | GAA (0.62) | GAAUSP2POLBTSHRMEN1 | |
| SCHEMBL14413865 | 0.84 | GAA (0.56) | GAAUSP2POLBTSHRMEN1 | |
| SCHEMBL19732924 | 0.83 | MEN1 (0.62) | GAAUSP2POLBTSHRMEN1 | |
| SCHEMBL19732925 | 0.83 | MEN1 (0.62) | GAAUSP2POLBTSHRMEN1 | |
| SCHEMBL19732943 | 0.83 | POLB (0.70) | GAAUSP2POLBTSHRMEN1 | |
| SCHEMBL19732942 | 0.83 | POLB (0.70) | GAAUSP2POLBTSHRMEN1 | |
| SCHEMBL19752654 | 0.83 | POLB (0.74) | GAAPOLBTSHRMEN1KMT2A | |
| SCHEMBL2951080 | 0.83 | POLB (0.74) | GAAPOLBTSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3260446-A1 | ENANTIOSELECTIVE SYNTHESIS OF DIHYDROPYRIMIDINONES AND HEXAHYDROPYRIMIDINONES | Universitat de les Illes Balears (ES) | 2017-12-27 | — | — | EP | disclosed |