Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19732960 | 1.00 | USP2 (0.56) | USP2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6348279 | 0.85 | HTT (0.57) | USP2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL19752713 | 0.85 | MEN1 (0.67) | MEN1KMT2AALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL19752712 | 0.85 | MEN1 (0.67) | MEN1KMT2AALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL19732955 | 0.80 | USP2 (0.79) | USP2MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL19732923 | 0.80 | USP2 (0.79) | USP2MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL13789190 | 0.80 | USP2 (0.79) | USP2MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL13425500 | 0.79 | GAA (0.46) | MEN1KMT2AALDH1A1POLB | |
| SCHEMBL3398109 | 0.77 | TP53 (0.44) | MEN1KMT2ATP53 | |
| SCHEMBL3398102 | 0.77 | TP53 (0.44) | MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3260446-A1 | ENANTIOSELECTIVE SYNTHESIS OF DIHYDROPYRIMIDINONES AND HEXAHYDROPYRIMIDINONES | Universitat de les Illes Balears (ES) | 2017-12-27 | — | — | EP | disclosed |