Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3398109 | 1.00 | TP53 (0.44) | TP53CTDSP1PDE1CKIF11ADORA2B | |
| SCHEMBL3362453 | 0.80 | PDE1C (0.39) | TP53CTDSP1PDE1CKIF11ADORA2B | |
| SCHEMBL3362451 | 0.80 | PDE1C (0.39) | TP53CTDSP1PDE1CKIF11ADORA2B | |
| SCHEMBL3362458 | 0.80 | PDE1C (0.39) | TP53CTDSP1PDE1CKIF11ADORA2B | |
| SCHEMBL19732959 | 0.77 | USP2 (0.56) | TP53MEN1KMT2A | |
| SCHEMBL19732960 | 0.77 | USP2 (0.56) | TP53MEN1KMT2A | |
| SCHEMBL6348279 | 0.77 | HTT (0.57) | TP53KIF11ADORA2BMEN1KMT2A | |
| SCHEMBL13425599 | 0.74 | TP53 (0.50) | TP53CTDSP1PDE1CL3MBTL1NPSR1 | |
| SCHEMBL7477778 | 0.70 | CA12 (0.41) | NPSR1GAA | |
| SCHEMBL13425500 | 0.69 | GAA (0.46) | L3MBTL1MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |