Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LAP3 | P28838 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16774481 | 1.00 | KMT2A (0.44) | KMT2AHTTCYP2C19TDP1L3MBTL1 | |
| SCHEMBL16774864 | 0.82 | NPC1 (0.44) | KMT2AHTTCYP2C19NPC1TSHR | |
| SCHEMBL16774770 | 0.82 | NPC1 (0.44) | KMT2AHTTCYP2C19NPC1TSHR | |
| SCHEMBL20128492 | 0.81 | NPC1 (0.43) | KMT2AHTTCYP2C19NPC1CA1 | |
| SCHEMBL20128498 | 0.81 | NPC1 (0.43) | KMT2AHTTCYP2C19NPC1CA1 | |
| SCHEMBL20132829 | 0.78 | HPRT1 (0.42) | HTTCYP2C19TDP1L3MBTL1NPC1 | |
| SCHEMBL20132791 | 0.78 | HPRT1 (0.42) | HTTCYP2C19TDP1L3MBTL1NPC1 | |
| SCHEMBL9068544 | 0.75 | CA1 (0.51) | HTTCYP2C19NPC1TSHRCA1 | |
| SCHEMBL4185933 | 0.75 | CA1 (0.51) | HTTCYP2C19NPC1TSHRCA1 | |
| SCHEMBL4185937 | 0.75 | CA1 (0.51) | HTTCYP2C19NPC1TSHRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2883858-B1 | METHOD FOR PRODUCING HEXAHYDROFUROFURANOL DERIVATIVE | SUMITOMO CHEMICAL CO (JP) | 2017-12-27 | — | — | EP | disclosed |