Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA7 | P43166 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9068544 | 1.00 | CA1 (0.51) | CA1CA2CA7CA9TSHR | |
| SCHEMBL4185937 | 1.00 | CA1 (0.51) | CA1CA2CA7CA9TSHR | |
| SCHEMBL25435936 | 0.96 | CA1 (0.49) | CA1CA2CA7CA9TSHR | |
| SCHEMBL11315619 | 0.89 | CA1 (0.49) | CA1CA2CA7CA9TSHR | |
| SCHEMBL11302178 | 0.89 | CA1 (0.49) | CA1CA2CA7CA9TSHR | |
| SCHEMBL15519785 | 0.88 | CA1 (0.47) | CA1CA2CA7CA9TSHR | |
| SCHEMBL11177231 | 0.88 | CA1 (0.47) | CA1CA2CA7CA9TSHR | |
| SCHEMBL9592045 | 0.87 | CA1 (0.50) | CA1CA2CA7CA9TSHR | |
| SCHEMBL9188557 | 0.85 | CA1 (0.66) | CA1CA2CA7CA9TSHR | |
| SCHEMBL9187215 | 0.85 | CA1 (0.66) | CA1CA2CA7CA9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4223765-A1 | 1,3-FATTY DIOL COMPOUNDS AND DERIVATIVES THEREOF | Genomatica, Inc. (US) | 2023-08-09 | — | — | EP | disclosed |
| EP-3795576-B1 | 1,3-FATTY DIOL COMPOUNDS AND GLYCOSYLATED DERIVATIVES THEREOF | GENOMATICA INC (US) | 2023-06-07 | — | — | EP | disclosed |
| EP-3795576-B1 | 1,3-FATTY DIOL COMPOUNDS AND GLYCOSYLATED DERIVATIVES THEREOF | GENOMATICA INC (US) | 2023-06-07 | — | — | EP | disclosed |
| US-11648315-B2 | Silvestrol antibody-drug conjugates and methods of use | GENENTECH, INC. (US) | 2023-05-16 | — | — | US | disclosed |
| US-11648315-B2 | Silvestrol antibody-drug conjugates and methods of use | GENENTECH, INC. (US) | 2023-05-16 | — | — | US | disclosed |
| CN-109476648-B | Sevelamer antibody-drug conjugates and methods of use | 豪夫迈·罗氏有限公司 | 2022-09-13 | — | — | CN | disclosed |
| US-20220098133-A1 | 1,3-Fatty Diol Compounds And Derivatives Thereof | AGAIN BIO APS (DK) | 2022-03-31 | — | — | US | disclosed |
| US-20220098133-A1 | 1,3-Fatty Diol Compounds And Derivatives Thereof | AGAIN BIO APS (DK) | 2022-03-31 | — | — | US | disclosed |
| US-11168046-B2 | 1,3-fatty diol compounds and derivatives thereof | GENOMATICA, INC. (US) | 2021-11-09 | — | — | US | disclosed |
| US-11168046-B2 | 1,3-fatty diol compounds and derivatives thereof | GENOMATICA, INC. (US) | 2021-11-09 | — | — | US | disclosed |
| EP-1061062-B1 | PROCESS FOR PRODUCING BUTANETRIOL DERIVATIVES | DAISO CO LTD (JP) | 2009-02-18 | — | — | EP | disclosed |
| US-20040024261-A1 | Process for preparing butanetriol derivative | DAISO CO., LTD. (JP) | 2004-02-05 | — | — | US | disclosed |
| US-6620977-B1 | Reacting 1,2,4-butanetriol in multiple steps with specified reagents using selective protection and deprotection of hydroxyl groups | DAISO CO., LTD. (JP) | 2003-09-16 | — | — | US | disclosed |
| EP-1061062-A1 | PROCESS FOR PRODUCING BUTANETRIOL DERIVATIVE | DAISO CO., LTD. (JP) | 2000-12-20 | — | — | EP | disclosed |
| US-5696263-A | Antiviral acyclic phosphonomethoxyalkylsubstituted alkenyl and alkynyl purine and pyrimidine derivatives | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1997-12-09 | — | — | US | disclosed |
| EP-0630381-B1 | ANTIVIRAL ACYCLIC PHOSPHONOMETHOXYALKYL SUBSTITUTED, ALKENYL AND ALKYNYL PURINE AND PYRIMIDINE DERIVATIVES | ACAD OF SCIENCE CZECH REPUBLIC (CZ) | 1997-04-09 | — | — | EP | disclosed |
| US-5530143-A | REDUCTION OF (3S)-3-HYDROXYOCTANEDIOIC DIESTER WITH COMPLEX HYDRIDE | BASF AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| EP-0487986-B1 | Process for the preparation of esters of (6s)-6,8-dihydroxyoctanoic acid | BASF AG (DE) | 1995-06-21 | — | — | EP | disclosed |
| WO-1993007157-A1 | ANTIVIRAL ACYCLIC PHOSPHONOMETHOXYALKYL SUBSTITUTED, ALKENYL AND ALKYNYL PURINE AND PYRIMIDINE DERIVATIVES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OFTHE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1993-04-15 | — | — | WO | disclosed |
| EP-0487986-A2 | Process for the preparation of esters of (6s)-6,8-dihydroxyoctanoic acid | BASF Aktiengesellschaft (DE) | 1992-06-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11648315-B2 | Silvestrol antibody-drug conjugates and methods of use | SHBG, EPCAM, ITGAV | CA1 1480/4885CA2 3109/4885CA7 2226/4885 |
| US-11168046-B2 | 1,3-fatty diol compounds and derivatives thereof | DGAT1, DGAT2, DSG1 | CA1 4200/4885CA2 4285/4885CA7 3666/4885 |
| US-20220098133-A1 | 1,3-Fatty Diol Compounds And Derivatives Thereof | DGAT1, DGAT2, DSG1 | CA1 4200/4885CA2 4285/4885CA7 3666/4885 |
| US-20040024261-A1 | Process for preparing butanetriol derivative | CYP4B1, CYP11B2, CYP11B1 | CA1 3367/4885CA2 4174/4885CA7 1754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.