Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F13A1 | P00488 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | TGM1 | P22735 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18745268 | 1.00 | F13A1 (0.32) | F13A1TGM2TGM1L3MBTL1SRC | |
| SCHEMBL15318856 | 1.00 | F13A1 (0.32) | F13A1TGM2TGM1L3MBTL1SRC | |
| SCHEMBL15318858 | 1.00 | F13A1 (0.32) | F13A1TGM2TGM1L3MBTL1SRC | |
| SCHEMBL16558938 | 0.93 | L3MBTL1 (0.32) | F13A1TGM2TGM1L3MBTL1 | |
| SCHEMBL15319742 | 0.88 | — | — | |
| SCHEMBL15319740 | 0.88 | — | — | |
| SCHEMBL19732977 | 0.88 | — | — | |
| SCHEMBL19732976 | 0.88 | — | — | |
| SCHEMBL15320958 | 0.87 | L3MBTL1 (0.33) | F13A1TGM2TGM1L3MBTL1 | |
| SCHEMBL15319764 | 0.86 | L3MBTL1 (0.33) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2834239-B1 | HETEROBICYCLIC COMPOUNDS AS BETA-LACTAMASE INHIBITORS | ENTASIS THERAPEUTICS LTD (GB) | 2017-12-27 | — | — | EP | disclosed |