Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25401332 | 0.86 | SPHK1 (0.32) | SPHK1 | |
| SCHEMBL13726741 | 0.86 | SPHK1 (0.32) | SPHK1 | |
| SCHEMBL25401336 | 0.86 | SPHK1 (0.32) | SPHK1 | |
| SCHEMBL23850149 | 0.85 | SPHK1 (0.35) | SPHK1 | |
| SCHEMBL15318921 | 0.85 | SPHK1 (0.35) | SPHK1 | |
| SCHEMBL3633420 | 0.85 | SPHK1 (0.35) | SPHK1 | |
| SCHEMBL4912532 | 0.85 | SPHK1 (0.35) | SPHK1 | |
| SCHEMBL23850147 | 0.85 | SPHK1 (0.35) | SPHK1 | |
| SCHEMBL25403981 | 0.82 | SPHK1 (0.30) | SPHK1 | |
| SCHEMBL8646545 | 0.79 | SPHK1 (0.37) | SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2834239-B1 | HETEROBICYCLIC COMPOUNDS AS BETA-LACTAMASE INHIBITORS | ENTASIS THERAPEUTICS LTD (GB) | 2017-12-27 | — | — | EP | disclosed |