SCHEMBL23850147

SCHEMBL23850147

CC(=O)[C@@H]1COC(C)(C)N1C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ SPHK1 Q9NYA1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23850149 1.00 SPHK1 (0.35) SPHK1
SCHEMBL15318921 0.88 SPHK1 (0.35) SPHK1
SCHEMBL4912532 0.88 SPHK1 (0.35) SPHK1
SCHEMBL3633420 0.88 SPHK1 (0.35) SPHK1
SCHEMBL19733005 0.85 SPHK1 (0.33) SPHK1
SCHEMBL25401336 0.82 SPHK1 (0.32) SPHK1
SCHEMBL13726741 0.82 SPHK1 (0.32) SPHK1
SCHEMBL25401332 0.82 SPHK1 (0.32) SPHK1
SCHEMBL8646545 0.82 SPHK1 (0.37) SPHK1
SCHEMBL19732991 0.82 SPHK1 (0.32) SPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230093692-A1 C10-Alkylene Substituted 13-Membered Macrolides and Uses Thereof ZIKANI THERAPEUTICS, INC. 2023-03-23 — — US disclosed
EP-3883647-A1 C10-ALKYLENE SUBSTITUTED 13-MEMBERED MACROLIDES AND USES THEREOF Zikani Therapeutics, Inc. (US) 2021-09-29 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230093692-A1 C10-Alkylene Substituted 13-Membered Macrolides and Uses Thereof RPS14, RPL17, RPN2 SPHK1 731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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