Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16552841 | 1.00 | BCL2 (0.32) | BCL2BCL2L1MCL1METMEN1 | |
| SCHEMBL15320118 | 1.00 | BCL2 (0.32) | BCL2BCL2L1MCL1METMEN1 | |
| SCHEMBL19733012 | 1.00 | BCL2 (0.32) | BCL2BCL2L1MCL1METMEN1 | |
| SCHEMBL19990062 | 0.91 | MET (0.34) | BCL2BCL2L1MCL1METMEN1 | |
| SCHEMBL15320316 | 0.91 | MET (0.33) | BCL2BCL2L1MCL1METMEN1 | |
| SCHEMBL19990063 | 0.91 | MET (0.34) | BCL2BCL2L1MCL1METMEN1 | |
| SCHEMBL29593959 | 0.91 | MET (0.33) | BCL2BCL2L1MCL1METMEN1 | |
| SCHEMBL16553194 | 0.91 | MET (0.33) | BCL2BCL2L1MCL1METMEN1 | |
| SCHEMBL19990061 | 0.91 | MET (0.34) | BCL2BCL2L1MCL1METMEN1 | |
| SCHEMBL19733022 | 0.90 | MEN1 (0.33) | METMEN1KMT2AHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2834239-B1 | HETEROBICYCLIC COMPOUNDS AS BETA-LACTAMASE INHIBITORS | ENTASIS THERAPEUTICS LTD (GB) | 2017-12-27 | — | — | EP | disclosed |