Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 5/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6058482 | 0.82 | DAO (0.42) | DAODPP4GPR35ALDH1A1HPGD | |
| SCHEMBL18701547 | 0.76 | GSK3B (0.42) | DAODPP4GPR35ALDH1A1HPGD | |
| SCHEMBL18701677 | 0.74 | ALDH1A1 (0.39) | DAODPP4GPR35ALDH1A1HPGD | |
| SCHEMBL8601488 | 0.73 | ALDH1A1 (0.31) | ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL18701671 | 0.72 | DAO (0.35) | DAODPP4 | |
| SCHEMBL18701608 | 0.72 | MCL1 (0.42) | DAODPP4GPR35ALDH1A1HPGD | |
| SCHEMBL18701838 | 0.72 | DAO (0.35) | DAODPP4 | |
| SCHEMBL8629628 | 0.72 | DAO (0.42) | DAODPP4GPR35ALDH1A1HPGD | |
| SCHEMBL18701546 | 0.70 | DAO (0.34) | DAODPP4GSK3B | |
| SCHEMBL18701752 | 0.70 | DAO (0.34) | DAODPP4GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074451-B1 | NOVEL POLYCYCLIC POLYMER COMPRISING THIOPHENE UNITS, A METHOD OF PRODUCING AND USES OF SUCH POLYMER | MERCK PATENT GMBH (DE) | 2017-12-27 | — | — | EP | disclosed |