Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 6/20 | 0.59 |
| ▸ | GSK3B | P49841 | 14/20 | 0.56 |
| ▸ | QPCT | Q16769 | 11/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127704 | 0.86 | IDH1 (0.70) | IDH1GSK3BQPCT | |
| SCHEMBL8163218 | 0.73 | GSK3B (0.81) | GSK3B | |
| SCHEMBL1128498 | 0.72 | GSK3B (0.52) | IDH1GSK3B | |
| SCHEMBL3781580 | 0.71 | GSK3B (0.66) | GSK3B | |
| SCHEMBL5754334 | 0.70 | GSK3B (0.67) | IDH1GSK3B | |
| SCHEMBL4689265 | 0.70 | GSK3B (0.50) | IDH1GSK3B | |
| SCHEMBL4691089 | 0.70 | GSK3B (0.50) | IDH1GSK3B | |
| SCHEMBL5757844 | 0.69 | GSK3B (0.67) | GSK3B | |
| SCHEMBL5752565 | 0.69 | GSK3B (0.54) | IDH1GSK3B | |
| SCHEMBL5754325 | 0.69 | GSK3B (0.69) | IDH1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2664669-B1 | TREATMENT OF PLURIPOTENT CELLS | JANSSEN BIOTECH INC (US) | 2017-12-27 | — | — | EP | claimed |