Sugi Predict

Sugi Predict / Compounds / SCHEMBL197331

SCHEMBL197331

SCHEMBL197331

O=S(=O)(Oc1ccccc1)c1ccc(Cl)cc1

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 2/20 0.85
▸ ENPP1 P22413 5/20 0.57
▸ ENPP3 O14638 4/20 0.57
▸ MEN1 O00255 2/20 0.55
▸ KMT2A Q03164 2/20 0.55
▸ PGR P06401 2/20 0.50
▸ TP53 P04637 1/20 0.50
▸ GAA P10253 1/20 0.50
▸ PPARG P37231 1/20 0.49
▸ CA1 P00915 2/20 0.48
▸ CA2 P00918 2/20 0.48
▸ CA9 Q16790 2/20 0.48
▸ ENPP2 Q13822 3/20 0.48
▸ APEX1 P27695 1/20 0.47
▸ ALDH1A1 P00352 2/20 0.46
▸ CYP3A4 P08684 2/20 0.46
▸ MAPK1 P28482 1/20 0.46
▸ LMNA P02545 1/20 0.45
▸ HTT P42858 1/20 0.45
▸ SMN1; SMN2 Q16637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28101402 0.98 TDP1 (0.82) TDP1ENPP1ENPP3MEN1KMT2A
SCHEMBL165491 0.92 TDP1 (1.00) TDP1ENPP1ENPP3MEN1KMT2A
SCHEMBL6912531 0.92 TDP1 (1.00) TDP1ENPP1ENPP3MEN1KMT2A
Chlorfenson SCHEMBL7194888 0.90 TDP1 (0.81) TDP1ENPP1ENPP3MEN1KMT2A
Chlorfenson SCHEMBL116752 0.90 TDP1 (0.81) TDP1ENPP1ENPP3MEN1KMT2A
SCHEMBL8600833 0.89 TDP1 (0.80) TDP1ENPP1ENPP3MEN1KMT2A
SCHEMBL7981247 0.85 TDP1 (0.73) TDP1ENPP1ENPP3KMT2ACA1
SCHEMBL19146 0.85 TDP1 (0.73) TDP1ENPP1ENPP3KMT2ACA1
SCHEMBL28934632 0.83 TDP1 (0.70) TDP1ENPP1ENPP3KMT2ACA1
SCHEMBL1674227 0.83 TDP1 (0.70) TDP1ENPP1ENPP3KMT2ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117186028-A Thiadiazole amide compound containing sulfonate structure, and preparation method and application thereof 贵州大学 2023-12-08 — — CN disclosed
CN-115947668-A Preparation method of polysubstituted indene derivative 广东工业大学 2023-04-11 — — CN disclosed
CN-114773238-B Phenylpropylidene acylated p-chlorobenzenesulfonyl ferulic acid ester derivative and preparation method and application thereof 南京大学 2023-03-24 — — CN disclosed
CN-114773238-A Phenylacryloyl acylated p-chlorophenyl sulfonyl ferulic acid ester derivatives, and preparation method and application thereof 南京大学 2022-07-22 — — CN disclosed
CN-109574891-B Synthetic method of triaryl-substituted alkenyl thioether compound 湖南医药学院 2020-06-30 — — CN disclosed
US-10362786-B2 Stable aqueous spore-containing formulation BAYER INTELLECTUAL PROPERTY GMBH (DE) 2019-07-30 — — US disclosed
CN-109574891-A A kind of synthetic method for the alkenyl sulfide compound that triaryl replaces 湖南医药学院 2019-04-05 — — CN disclosed
US-8293905-B2 Bipyridine compound, transition metal complex, and method for production of conjugated aromatic compound using the transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-23 — — US disclosed
US-8088883-B2 Transition metal complex and process for producing conjugated aromatic compound using the transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-03 — — US disclosed
US-20110046336-A1 TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX SUMITOMO CHEMICAL COMPANY, LIMITED 2011-02-24 — — US disclosed
CN-101827854-A Transition metal complex and method for producing conjugated aromatic compound using same SUMITOMO CHEMICAL CO 2010-09-08 — — CN disclosed
US-20100184978-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-07-22 — — US disclosed
CN-101772508-A Bipyridine compound, transition metal complex, and method for production of conjugated aromatic compound using the transition metal complex SUMITOMO CHEMICAL CO 2010-07-07 — — CN disclosed
EP-2192124-A1 TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND WITH THE TRANSITION METAL COMPLEX Sumitomo Chemical Company, Limited (JP) 2010-06-02 — — EP disclosed
EP-2172470-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX Sumitomo Chemical Company, Limited (JP) 2010-04-07 — — EP disclosed
CN-101394853-A Use of pyrazolo [1, 5-a ] pyrimidin-7-ylamine derivatives in the treatment of neurological disorders NOVARTIS AG (CH) 2009-03-25 — — CN disclosed
US-5441743-A In thermoplastic or thermosetting binder BATTELLE MEMORIAL INSTITUTE (US) 1995-08-15 — — US disclosed
US-4433156-A Process for preparing fluoran derivatives FUJI PHOTO FILM CO., LTD. (JP) 1984-02-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110046336-A1 TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX C9, C5, AP1M1 TDP1 3931/4885ENPP1 4661/4885ENPP3 4769/4885
US-20100184978-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX C9, C5, AP2M1 TDP1 4012/4885ENPP1 4529/4885ENPP3 4712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.