Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.80 |
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.56 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.49 |
| ▸ | PARL | Q9H300 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL197331 | 0.89 | TDP1 (0.85) | TDP1APEX1ENPP1ENPP3MEN1 | |
| SCHEMBL6912531 | 0.89 | TDP1 (1.00) | TDP1APEX1ENPP1ENPP3MEN1 | |
| SCHEMBL165491 | 0.89 | TDP1 (1.00) | TDP1APEX1ENPP1ENPP3MEN1 | |
| SCHEMBL28101402 | 0.87 | TDP1 (0.82) | TDP1APEX1ENPP1ENPP3MEN1 | |
| SCHEMBL8442031 | 0.87 | TDP1 (0.58) | TDP1APEX1MEN1KMT2ACA2 | |
| SCHEMBL10950314 | 0.87 | TDP1 (0.58) | TDP1APEX1MEN1KMT2ACA2 | |
| SCHEMBL2058543 | 0.87 | TDP1 (0.69) | TDP1APEX1ENPP1ENPP3MEN1 | |
| Chlorfenson SCHEMBL116752 | 0.87 | TDP1 (0.81) | TDP1APEX1ENPP1ENPP3MEN1 | |
| Chlorfenson SCHEMBL7194888 | 0.87 | TDP1 (0.81) | TDP1APEX1ENPP1ENPP3MEN1 | |
| SCHEMBL17287655 | 0.85 | ENPP3 (0.63) | TDP1APEX1ENPP1ENPP3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508424-B1 | Method for preparing sulfones | SANKO KAIHATSU KAGAKU KENK (JP) | 1998-02-04 | — | — | EP | disclosed |
| US-5235084-A | METHOD FOR PREPARING SULFONES | SANKO KAIHATSU KAGAKU KENKYUSHO (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0508424-A2 | Method for preparing sulfones | Sanko Kaihatsu Kagaku Kenkyusho (JP) | 1992-10-14 | — | — | EP | disclosed |