Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.75 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.75 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.75 |
| ▸ | SHBG | P04278 | 1/20 | 0.75 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.75 |
| ▸ | GABRP | O00591 | 2/20 | 0.66 |
| ▸ | GABRD | O14764 | 2/20 | 0.66 |
| ▸ | G6PD | P11413 | 2/20 | 0.66 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.66 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.66 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.66 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.66 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.66 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.66 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19750430 | 1.00 | LMNA (0.75) | LMNAGPBAR1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL18575975 | 1.00 | LMNA (0.75) | LMNAGPBAR1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL15426614 | 1.00 | LMNA (0.75) | LMNAGPBAR1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL19253304 | 1.00 | LMNA (0.75) | LMNAGPBAR1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL14046194 | 1.00 | LMNA (0.75) | LMNAGPBAR1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL15426612 | 1.00 | LMNA (0.75) | LMNAGPBAR1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL19253297 | 1.00 | LMNA (0.75) | LMNAGPBAR1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL19750433 | 1.00 | LMNA (0.75) | LMNAGPBAR1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL17693865 | 1.00 | LMNA (0.75) | LMNAGPBAR1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL18335032 | 1.00 | LMNA (0.75) | LMNAGPBAR1CYP3A4CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3260462-A1 | AMPHIPHILIC COMPOUNDS WITH NEUROPROTECTIVE PROPERTIES | Ustav Organicke Chemie A Biochemie Av Cr, V.v.i. (CZ) | 2017-12-27 | — | — | EP | disclosed |