Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2668038 | 0.76 | TSHR (0.49) | TSHRALDH1A1HTTMAPTCYP1A2 | |
| SCHEMBL7001023 | 0.75 | GAA (0.56) | CYP3A4GAATHRBTSHRTDP1 | |
| SCHEMBL1771537 | 0.75 | CYP3A4 (0.56) | CYP3A4GAATHRBTSHRTDP1 | |
| SCHEMBL30873107 | 0.75 | CYP3A4 (0.56) | CYP3A4GAATHRBTSHRTDP1 | |
| SCHEMBL588348 | 0.75 | CYP3A4 (0.63) | CYP3A4GAATHRBTSHRTDP1 | |
| SCHEMBL5222516 | 0.74 | CYP3A4 (0.53) | CYP3A4GAATHRBTSHRTDP1 | |
| SCHEMBL19733667 | 0.73 | L3MBTL1 (0.48) | GAAALDH1A1HTTMAPTPOLB | |
| SCHEMBL14671132 | 0.73 | CYP2C19 (0.45) | GAAALDH1A1HTTMAPTCYP1A2 | |
| SCHEMBL2566274 | 0.73 | CYP3A4 (0.53) | CYP3A4GAATHRBTSHRTDP1 | |
| SCHEMBL15338405 | 0.72 | TSHR (0.50) | CYP3A4TSHRALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170360952-A1 | BIOMOLECULE CONJUGATES | CELGENE CORPORATION | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170360952-A1 | BIOMOLECULE CONJUGATES | DNPEP, NAPA, NCL | CYP3A4 3479/4885GAA 438/4885THRB 3978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.