Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3086675 | 0.84 | — | — | |
| SCHEMBL18924784 | 0.80 | — | — | |
| SCHEMBL6823774 | 0.78 | ADH1B (0.35) | — | |
| SCHEMBL14138921 | 0.72 | SMYD3 (0.33) | SMYD3KDM4EKMT2A | |
| SCHEMBL10641279 | 0.72 | MAPK1 (0.32) | KMT2A | |
| SCHEMBL23667165 | 0.72 | — | — | |
| SCHEMBL17780232 | 0.71 | KDM4E (0.38) | SMYD3KDM4EKMT2A | |
| SCHEMBL22779734 | 0.71 | — | — | |
| SCHEMBL21551515 | 0.71 | SMYD3 (0.44) | SMYD3KDM4EKMT2A | |
| SCHEMBL1313231 | 0.71 | SMYD3 (0.44) | SMYD3KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017216726-A1 | SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-12-21 | — | — | WO | disclosed |
| WO-2017216727-A1 | SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-12-21 | — | — | WO | disclosed |