Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29658743 | 0.87 | — | — | |
| SCHEMBL19717478 | 0.87 | — | — | |
| SCHEMBL19734432 | 0.76 | APP (0.38) | PTGS2 | |
| SCHEMBL19734434 | 0.76 | NPC1 (0.33) | PTGS2 | |
| SCHEMBL29658493 | 0.76 | TDP1 (0.34) | PTGS2 | |
| SCHEMBL19716964 | 0.76 | TDP1 (0.34) | PTGS2 | |
| SCHEMBL29658697 | 0.72 | CES2 (0.42) | PTGS2 | |
| SCHEMBL19717706 | 0.72 | CES2 (0.42) | PTGS2 | |
| SCHEMBL19717609 | 0.71 | CCNC (0.38) | — | |
| SCHEMBL29658527 | 0.71 | CCNC (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017216726-A1 | SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-12-21 | — | — | WO | disclosed |
| WO-2017216727-A1 | SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-12-21 | — | — | WO | disclosed |