Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | BCL2 | P10415 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.62 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.62 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29408635 | 1.00 | PTPN1 (0.64) | PTPN1KMT2ABCL2MEN1MCL1 | |
| SCHEMBL14163443 | 0.89 | KMT2A (0.78) | PTPN1KMT2ABCL2MEN1MCL1 | |
| SCHEMBL25997992 | 0.89 | MAPT (0.67) | KMT2ABCL2MEN1MCL1BCL2L1 | |
| SCHEMBL22092338 | 0.88 | MCL1 (0.67) | PTPN1KMT2ABCL2MEN1MCL1 | |
| SCHEMBL19736247 | 0.85 | MAPT (0.69) | PTPN1KMT2ABCL2MEN1MCL1 | |
| SCHEMBL29408609 | 0.85 | MAPT (0.69) | PTPN1KMT2ABCL2MEN1MCL1 | |
| SCHEMBL15709086 | 0.80 | MEN1 (0.60) | KMT2ABCL2MEN1MCL1BCL2L1 | |
| SCHEMBL15709085 | 0.80 | MEN1 (0.60) | KMT2ABCL2MEN1MCL1BCL2L1 | |
| SCHEMBL6884827 | 0.79 | PTPN1 (0.67) | PTPN1KMT2ABCL2MEN1MAPT | |
| SCHEMBL7485788 | 0.79 | PTPN1 (0.55) | PTPN1KMT2ABCL2MEN1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190307729-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS FOR USE THEREOF | VERSITECH LIMITED (HK) | 2019-10-10 | — | — | US | disclosed |
| WO-2017215552-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS FOR USE THEREOF | THE UNIVERSITY OF HONG KONG (CN) | 2017-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190307729-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS FOR USE THEREOF | NRDC, NISCH, NEK5 | PTPN1 4259/4885KMT2A 4486/4885BCL2 3042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.