Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | CRHBP | P24387 | 1/20 | 0.69 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.65 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.60 |
| ▸ | BCL2 | P10415 | 5/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.60 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.60 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | BCL2L2 | Q92843 | 3/20 | 0.56 |
| ▸ | DUSP22 | Q9NRW4 | 1/20 | 0.55 |
| ▸ | BAD | Q92934 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19736247 | 1.00 | MAPT (0.69) | MAPTMEN1KMT2AALDH1A1CRHBP | |
| SCHEMBL25997992 | 0.86 | MAPT (0.67) | MAPTMEN1KMT2AALDH1A1CRHBP | |
| SCHEMBL17769038 | 0.86 | MEN1 (0.73) | MAPTMEN1KMT2AALDH1A1CRHBP | |
| SCHEMBL29408635 | 0.85 | PTPN1 (0.64) | MAPTMEN1KMT2AALDH1A1PTPN1 | |
| SCHEMBL19736048 | 0.85 | PTPN1 (0.64) | MAPTMEN1KMT2AALDH1A1PTPN1 | |
| SCHEMBL6884827 | 0.84 | PTPN1 (0.67) | MAPTMEN1KMT2AALDH1A1CRHBP | |
| SCHEMBL6884831 | 0.84 | PTPN1 (0.67) | MAPTMEN1KMT2AALDH1A1CRHBP | |
| SCHEMBL15709086 | 0.80 | MEN1 (0.60) | MAPTMEN1KMT2AALDH1A1CRHBP | |
| SCHEMBL15709085 | 0.80 | MEN1 (0.60) | MAPTMEN1KMT2AALDH1A1CRHBP | |
| SCHEMBL18103043 | 0.78 | MAPT (0.75) | MAPTMEN1KMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220378751-A1 | INHIBITING DIHYDROFOLATE REDUCTASE IN A MICROORGANISM | VERSITECH LIMITED (HK) | 2022-12-01 | — | — | US | disclosed |
| CN-109414432-B | Antimicrobial compounds and methods of use thereof | 港大科桥有限公司 | 2022-03-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220378751-A1 | INHIBITING DIHYDROFOLATE REDUCTASE IN A MICROORGANISM | DHFR, BLVRB, QDPR | MAPT 2174/4885MEN1 3181/4885KMT2A 1948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.