Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.79 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.79 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.75 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.69 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.69 |
| ▸ | GFER | P55789 | 1/20 | 0.69 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29408629 | 1.00 | MEN1 (1.00) | MEN1POLBKMT2AAKR1B1PTPN1 | |
| SCHEMBL29408643 | 0.96 | MEN1 (0.93) | MEN1POLBKMT2AAKR1B1PTPN1 | |
| SCHEMBL19736249 | 0.96 | MEN1 (0.93) | MEN1POLBKMT2AAKR1B1PTPN1 | |
| SCHEMBL7146819 | 0.94 | MEN1 (0.90) | MEN1POLBKMT2AAKR1B1PTPN1 | |
| SCHEMBL7146815 | 0.94 | MEN1 (0.90) | MEN1POLBKMT2AAKR1B1PTPN1 | |
| SCHEMBL29408620 | 0.92 | MEN1 (0.85) | MEN1POLBKMT2AAKR1B1PTPN1 | |
| SCHEMBL19736087 | 0.92 | MEN1 (0.85) | MEN1POLBKMT2AAKR1B1PTPN1 | |
| SCHEMBL5217062 | 0.92 | ADAMTS5 (0.89) | MEN1POLBKMT2AAKR1B1PTPN1 | |
| SCHEMBL5217054 | 0.92 | ADAMTS5 (0.89) | MEN1POLBKMT2AAKR1B1PTPN1 | |
| SCHEMBL25992293 | 0.92 | MEN1 (0.85) | MEN1POLBKMT2AAKR1B1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190307729-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS FOR USE THEREOF | VERSITECH LIMITED (HK) | 2019-10-10 | — | — | US | disclosed |
| WO-2017215552-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS FOR USE THEREOF | THE UNIVERSITY OF HONG KONG (CN) | 2017-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190307729-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS FOR USE THEREOF | NRDC, NISCH, NEK5 | MEN1 1047/4885POLB 1616/4885KMT2A 4486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.