SCHEMBL19736446

SCHEMBL19736446

COC(=O)C1CCC(=O)NC1=O

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 19/20 0.52
DDB1 Q16531 16/20 0.52
IKZF3 Q9UKT9 1/20 0.38
CYP1A2 P05177 1/20 0.38
HIF1A Q16665 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11022447 0.81 TSHR (0.39) CRBNDDB1CYP1A2HIF1A
SCHEMBL10832062 0.81 CRBN (0.43) CRBNDDB1
SCHEMBL9163502 0.81 DDB1 (0.48) CRBNDDB1
Benzene SCHEMBL27893007 0.76 TSHR (0.43) CRBNDDB1CYP1A2HIF1A
SCHEMBL10832091 0.76 CRBN (0.56) CRBNDDB1IKZF3
SCHEMBL19605813 0.76 CRBN (0.51) CRBNDDB1IKZF3CYP1A2
SCHEMBL28505048 0.76 CRBN (0.56) CRBNDDB1IKZF3
SCHEMBL28506463 0.76 CRBN (0.56) CRBNDDB1IKZF3
SCHEMBL23855133 0.75 CRBN (0.50) CRBNDDB1IKZF3
Hydrochloric Acid SCHEMBL28859494 0.75 CRBN (0.54) CRBNDDB1IKZF3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170362155-A1 CIRCULAR ECONOMY METHODS OF PREPARING UNSATURATED COMPOUNDS INTERNATIONAL FLAVORS AND FRAGRANCES INC. 2017-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170362155-A1 CIRCULAR ECONOMY METHODS OF PREPARING UNSATURATED COMPOUNDS FADS1, SCD, FASN CRBN 1673/4885DDB1 2863/4885IKZF3 1526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.