SCHEMBL19737232

SCHEMBL19737232

CC(C)(C)OCCNC(=N)c1ccc(OCCOC(C)(C)C)s1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CPT2 P23786 1/20 0.32
CPT1A P50416 1/20 0.32
CPT1B Q92523 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20925876 0.77 HPGD (0.49) CPT2CPT1ACPT1B
SCHEMBL10859988 0.77 CPT2 (0.43) CPT2CPT1ACPT1B
SCHEMBL20912880 0.74 HDAC3 (0.39) CPT2CPT1ACPT1B
SCHEMBL10896745 0.69 CCNE2 (0.39) CPT2CPT1ACPT1B
SCHEMBL10857094 0.59 MAPT (0.40)
SCHEMBL10861492 0.58 CCNE2 (0.34)
SCHEMBL10860219 0.57 NPSR1 (0.46) CPT2CPT1ACPT1B
SCHEMBL12530457 0.57 MAPK1 (0.30)
SCHEMBL5128013 0.57 CA12 (0.31)
SCHEMBL10061719 0.57 MAPK1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017215588-A1 DIHYDROPYRAZOLE AZEPINE COMPOUND SERVING AS AKT INHIBITOR 南京明德新药研发股份有限公司 2017-12-21 WO disclosed