Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESRRA | P11474 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19737507 | 0.91 | HTR6 (0.71) | HTR6L3MBTL1CA12CA1CA2 | |
| SCHEMBL19737480 | 0.88 | HTR6 (0.56) | HTR6L3MBTL1CA12CA1CA2 | |
| SCHEMBL19737373 | 0.88 | HTR6 (0.59) | HTR6L3MBTL1CA12CA1CA2 | |
| Dimethylamine SCHEMBL21222481 | 0.86 | HTR6 (0.64) | HTR6L3MBTL1CA12CA1CA2 | |
| SCHEMBL21222635 | 0.84 | HTR6 (0.55) | HTR6L3MBTL1CA12CA1CA2 | |
| SCHEMBL21233248 | 0.83 | HTR6 (0.56) | HTR6L3MBTL1CA12CA1CA2 | |
| SCHEMBL19737629 | 0.82 | HTR6 (0.58) | HTR6L3MBTL1CYP3A4CYP2D6HTR2A | |
| SCHEMBL19737377 | 0.80 | HTR6 (0.59) | HTR6L3MBTL1CA12CA1CA2 | |
| SCHEMBL19737552 | 0.80 | HTR6 (0.55) | HTR6L3MBTL1CA12CA1CA2 | |
| SCHEMBL19737475 | 0.79 | TNFSF11 (0.52) | HTR6L3MBTL1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10689342-B2 | Aza-tanshinone derivatives, process for their preparation and their use in therapy | UNIVERSITA' DEGLI STUDI DI TRENTO (IT) | 2020-06-23 | — | — | US | disclosed |
| US-10689342-B2 | Aza-tanshinone derivatives, process for their preparation and their use in therapy | UNIVERSITA' DEGLI STUDI DI TRENTO (IT) | 2020-06-23 | — | — | US | disclosed |
| US-20190241516-A1 | AZA-TANSHINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THERAPY | UNIVERSITA' DEGLI STUDI DI TRENTO (IT) | 2019-08-08 | — | — | US | disclosed |
| US-20190241516-A1 | AZA-TANSHINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THERAPY | UNIVERSITA' DEGLI STUDI DI TRENTO (IT) | 2019-08-08 | — | — | US | disclosed |
| WO-2017216732-A1 | AZA-TANSHINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THERAPY | UNIVERSITA' DEGLI STUDI DI MILANO (IT) | 2017-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190241516-A1 | AZA-TANSHINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THERAPY | AZI2, TPMT, TYMS | HTR6 1922/4885L3MBTL1 4885/4885CA12 3782/4885 |
| US-10689342-B2 | Aza-tanshinone derivatives, process for their preparation and their use in therapy | AZI2, TPMT, TYMS | HTR6 1922/4885L3MBTL1 4885/4885CA12 3782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.