Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19725197 | 0.93 | NR1H4 (0.60) | NR1H4HSD17B13 | |
| SCHEMBL19725196 | 0.90 | NR1H4 (0.58) | NR1H4HSD17B13 | |
| SCHEMBL19738335 | 0.90 | NR1H4 (0.58) | NR1H4HSD17B13 | |
| SCHEMBL24357787 | 0.87 | NR1H4 (0.52) | NR1H4HSD17B13 | |
| SCHEMBL24357886 | 0.85 | NR1H4 (0.49) | NR1H4HSD17B13 | |
| SCHEMBL19738295 | 0.84 | NR1H4 (0.53) | NR1H4HSD17B13 | |
| SCHEMBL19738568 | 0.81 | NR1H4 (0.46) | NR1H4HSD17B13 | |
| SCHEMBL24357788 | 0.81 | NR1H4 (0.53) | NR1H4HSD17B13 | |
| SCHEMBL19620247 | 0.80 | NR1H4 (0.58) | NR1H4HSD17B13 | |
| SCHEMBL18724807 | 0.78 | NR1H4 (0.55) | NR1H4HSD17B13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3730487-B1 | AZETIDINE DERIVATIVES AS FXR (NR1H4) MODULATORS | GILEAD SCIENCES INC (US) | 2022-04-27 | — | — | EP | disclosed |
| WO-2017218337-A1 | FXR (NR1H4) MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2017-12-21 | — | — | WO | disclosed |