Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL342564 | 0.95 | — | — | |
| SCHEMBL5072658 | 0.92 | — | — | |
| SCHEMBL28436707 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL27492535 | 0.90 | — | — | |
| Iodide SCHEMBL20603123 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL342565 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL15994074 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL7112379 | 0.90 | — | — | |
| Iodide SCHEMBL28453451 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL10589248 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 919 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383418-B1 | SLC45A2 PEPTIDES FOR IMMUNOTHERAPY | UNIV TEXAS (US) | 2021-10-20 | — | — | EP | disclosed |
| US-20210170002-A1 | SLC45A2 PEPTIDES FOR IMMUNOTHERAPY | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2021-06-10 | — | — | US | disclosed |
| CN-112662561-A | Normal-temperature bacteria ribonucleic acid protective agent and preparation method and application thereof | 中农新科(苏州)有机循环研究院有限公司 | 2021-04-16 | — | — | CN | disclosed |
| US-20190169262-A1 | SLC45A2 PEPTIDES FOR IMMUNOTHERAPY | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2019-06-06 | — | — | US | disclosed |
| US-20170368171-A1 | Diagnostics and Therapeutics for Diseases Associated With G-Protein Coupled Receptor AdipoR2 (AdipoR2) | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2017-12-28 | — | — | US | disclosed |
| EP-2520302-B1 | Stromal cell-derived factor-1 mediates stem cell homing and tissue regeneration in ischemic cardiomyopathy | CLEVELAND CLINIC FOUNDATION (US) | 2016-08-17 | — | — | EP | disclosed |
| EP-2102357-B1 | LTBP2 AS A BIOMARKER, THERAPEUTIC AND DIAGNOSTIC TARGET | BAYER IP GMBH (DE) | 2013-11-27 | — | — | EP | disclosed |
| US-20130089552-A1 | ACYLGLYCEROL ACYLTRANSFERASE-LIKE PROTEIN MGAT-X1 AND USES THEREOF | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-04-11 | — | — | US | disclosed |
| EP-1630229-B1 | Melanoma antigens | US HEALTH (US) | 2013-04-03 | — | — | EP | disclosed |
| US-8343745-B2 | Acylglycerol acyltransferase-like protein MGAT-X1 and uses thereof | Bayer Pharma AG (DE) | 2013-01-01 | — | — | US | disclosed |
| US-4963484-A | Double stranded DNA of 309 nucleotides is immunologically reactive with monoclonal antibody | DANA-FARBER CANCER INSTITUTE, INC. (US) | 1990-10-16 | — | — | US | disclosed |
| US-4898814-A | A cDNA clone for human tyrosinase | DONALD GUTHRIE FOUNDATION FOR MEDICAL RESEARCH, INC. (US) | 1990-02-06 | — | — | US | disclosed |
| EP-0290504-A4 | A cDNA CLONE FOR HUMAN TYROSINASE. | GUTHRIE DONALD FOUND MED RES (US) | 1989-09-19 | — | — | EP | disclosed |
| WO-1989007107-A1 | GENETICALLY ENGINEERED POLYPEPTIDES WITH DETERMINANTS OF THE HUMAN DF3 BREAST CARCINOMA-ASSOCIATED ANTIGEN | DANA-FARBER CANCER INSTITUTE (US) | 1989-08-10 | — | — | WO | disclosed |
| EP-0290504-A1 | A cDNA CLONE FOR HUMAN TYROSINASE | DONALD GUTHRIE FOUNDATION FOR MEDICAL RESEARCH, INC. (US) | 1988-11-17 | — | — | EP | disclosed |
| WO-1988002372-A1 | A cDNA CLONE FOR HUMAN TYROSINASE | DONALD GUTHRIE FOUNDATION FOR MEDICAL RESEARCH, IN (US) | 1988-04-07 | — | — | WO | disclosed |
| EP-0259615-A1 | Human low affinity Fc epsilon-receptor, the isolation, the recombinant preparation and purification thereof | Kishimoto, Tadamitsu, Prof. (JP) | 1988-03-16 | — | — | EP | disclosed |
| EP-0258489-A1 | Human low affinity FC epsilon-receptor, the isolation and purification thereof | Kishimoto, Tadamitsu, Prof. (JP) | 1988-03-09 | — | — | EP | disclosed |
| EP-0258492-A1 | Human low affinity Fc epsilon-receptor, the isolation, the recombinant preparation and purification thereof | Kishimoto, Tadamitsu, Prof. (JP) | 1988-03-09 | — | — | EP | disclosed |
| EP-0257114-A1 | Human low affinity Fc epsilon-receptor, the isolation and purification thereof | Kishimoto, Tadamitsu, Prof. (JP) | 1988-03-02 | — | — | EP | disclosed |