SCHEMBL1974047

SCHEMBL1974047

Cc1ccc(OP(O)(=S)Oc2ccc(C)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.54
CYP3A4 P08684 1/20 0.54
LMNA P02545 2/20 0.46
ACHE P22303 2/20 0.44
PTK2B Q14289 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
THRB P10828 1/20 0.39
NPC1 O15118 1/20 0.39
HPGD P15428 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
BLM P54132 1/20 0.38
MMP13 P45452 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TEAD4 Q15561 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28761583 0.89 CYP3A4 (0.48) TSHRCYP3A4LMNAACHEPTK2B
SCHEMBL6691437 0.86 TSHR (0.54) TSHRCYP3A4LMNAACHEPTK2B
SCHEMBL869948 0.82 TSHR (0.50) TSHRCYP3A4LMNAACHEPTK2B
SCHEMBL258632 0.80 CYP3A4 (0.58) TSHRCYP3A4LMNAACHEALDH1A1
SCHEMBL28462057 0.79 CYP3A4 (0.47) TSHRCYP3A4LMNAACHEPTK2B
SCHEMBL790223 0.76 CYP3A4 (0.54) TSHRCYP3A4LMNAACHEALDH1A1
SCHEMBL11661650 0.76 CYP3A4 (0.54) TSHRCYP3A4LMNAACHEALDH1A1
SCHEMBL157866 0.76 TSHR (0.67) TSHRCYP3A4LMNAACHEPTK2B
SCHEMBL5850244 0.76 CYP3A4 (0.54) TSHRCYP3A4LMNAACHEALDH1A1
Zinc Ion SCHEMBL7267876 0.76 CYP3A4 (0.54) TSHRCYP3A4LMNAACHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220193695-A1 Collector Composition and Methods of Using Thereof KRATON POLYMERS LLC (US) 2022-06-23 US claimed
US-9302274-B2 Collector compositions and methods of using the same CYTEC TECHNOLOGY CORP. (US) 2016-04-05 US claimed
US-9302272-B2 Froth flotation processes CYTEC TECHNOLOGY CORP. (US) 2016-04-05 US claimed
EP-2768618-A2 FROTH FLOTATION PROCESSES Cytec Technology Corp. (US) 2014-08-27 EP claimed
EP-2768616-A2 COLLECTOR COMPOSITIONS AND METHODS OF USING THE SAME Cytec Technology Corp. (US) 2014-08-27 EP claimed
WO-2013059258-A2 COLLECTOR COMPOSITIONS AND METHODS OF USING THE SAME CYTEC TECHNOLOGY CORP. (US) 2013-04-25 WO claimed
WO-2013059259-A2 FROTH FLOTATION PROCESSES CYTEC TECHNOLOGY CORP. (US) 2013-04-25 WO claimed
US-20130092604-A1 Froth Flotation Processes CYTEC TECHNOLOGY CORP. (US) 2013-04-18 US claimed
US-20130092603-A1 Collector Compositions and Methods of Using the Same CYTEC TECHNOLOGY CORP. (US) 2013-04-18 US claimed
US-12415190-B2 Collector composition and methods of using thereof Kraton Corporation (US) 2025-09-16 US disclosed
EP-3691992-B1 PROCESSES FOR REMOVING HEAVY METALS FROM PHOSPHORIC ACID SOLUTIONS CYTEC IND INC (US) 2022-07-06 EP disclosed
US-20220193695-A1 Collector Composition and Methods of Using Thereof KRATON POLYMERS LLC (US) 2022-06-23 US disclosed
US-10293345-B2 Collector compositions and methods of using thereof KRATON CHEMICAL, LLC (US) 2019-05-21 US disclosed
US-20170128955-A1 Collector Compositions and Methods of Using Thereof ARIZONA CHEMICAL COMPANY, LLC (US) 2017-05-11 US disclosed
EP-0531585-B1 Oil additive concentrates and lubricants of enhanced performance capabilities ETHYL PETROLEUM ADDITIVES LTD (GB) 1998-11-04 EP disclosed
US-5464549-A Oil soluble dispersants suitable for use in fuels and lubricants ETHYL CORPORATION (US) 1995-11-07 US disclosed
US-5358652-A Using 3,5-dihydrocarbyl-4-hydroxybenzylamine compound ETHYL PETROLEUM ADDITIVES, LIMITED (GB) 1994-10-25 US disclosed
US-5241003-A Post-treated polyisobutenyl succinimide; crankcase, transmission oils ETHYL PETROLEUM ADDITIVES, INC. (US) 1993-08-31 US disclosed
EP-0531585-A1 Oil additive concentrates and lubricants of enhanced performance capabilities ETHYL PETROLEUM ADDITIVES LIMITED (GB) 1993-03-17 EP disclosed
US-5137980-A Reacting polyisobutene with aacidic reactant; super atmospheric pressure; low tar rating ETHYL PETROLEUM ADDITIVES, INC. (US) 1992-08-11 US disclosed