SCHEMBL869948

SCHEMBL869948

Cc1ccc(OP(O)(=S)S)cc1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
CYP3A4 P08684 1/20 0.50
LMNA P02545 3/20 0.43
ACHE P22303 2/20 0.41
PTK2B Q14289 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
MAPT P10636 2/20 0.37
KDM4E B2RXH2 1/20 0.37
GAA P10253 1/20 0.37
THRB P10828 1/20 0.37
TEAD4 Q15561 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6692402 0.82 CYP3A4 (0.54) TSHRCYP3A4LMNAACHEMAPT
SCHEMBL1691989 0.82 CYP3A4 (0.54) TSHRCYP3A4LMNAACHEMAPT
SCHEMBL6691437 0.82 TSHR (0.54) TSHRCYP3A4LMNAACHEPTK2B
SCHEMBL1974047 0.82 TSHR (0.54) TSHRCYP3A4LMNAACHEPTK2B
SCHEMBL258632 0.81 CYP3A4 (0.58) TSHRCYP3A4LMNAACHEMAPT
Ammonia Solution, Strong SCHEMBL8859771 0.80 CYP3A4 (0.52) TSHRCYP3A4LMNAACHEMAPT
SCHEMBL28462057 0.79 CYP3A4 (0.47) TSHRCYP3A4LMNAACHEPTK2B
Zinc Ion SCHEMBL2989295 0.78 CYP3A4 (0.50) TSHRCYP3A4LMNAACHEMAPT
SCHEMBL11700545 0.78 TSHR (0.61) TSHRCYP3A4LMNAACHEPTK2B
SCHEMBL8830439 0.78 CYP1A1 (0.39) TSHRCYP3A4LMNAMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8398947-B2 Separation of diamond from gangue minerals MINERAL AND COAL TECHNOLOGIES, INC. (US) 2013-03-19 US disclosed
US-20120076717-A1 Separation of Diamond from Gangue Minerals YOON ROE HOAN (US) 2012-03-29 US disclosed
US-8007754-B2 Separation of diamond from gangue minerals MINERAL AND COAL TECHNOLOGIES, INC. (US) 2011-08-30 US disclosed
US-20060251566-A1 Separation of diamond from gangue minerals MINERAL AND COAL TECHNOLOGIES, INC. 2006-11-09 US disclosed
WO-2006084170-A2 IMPROVING THE SEPARATION OF DIAMOND FROM GANGUE MINERALS MINERAL AND COAL TECHNOLOGIES, INC. (US) 2006-08-10 WO disclosed
US-20040204325-A1 Transmission fluid compositions for automobiles NIPPON OIL CORPORATION 2004-10-14 US disclosed
US-20040192562-A1 Lubricating oil composition NIPPON OIL CORPORATION 2004-09-30 US disclosed
US-5942470-A OIL SOLUBLE SULFUR CONTAINING PRESSURE AND ANTI-WEAR AGENT, AMINE SALT OF PHOSPHORUS ESTER, SUCCINIMIDE, AND ASHLESS DISPERSANTS ETHYL PETROLEUM ADDITIVES, INC. (US) 1999-08-24 US disclosed
EP-0459656-B1 Lubricant compositions ETHYL PETROLEUM ADDITIVES INC (US) 1995-09-20 EP disclosed
EP-0459656-A1 Lubricant compositions ETHYL PETROLEUM ADDITIVES, INC. (US) 1991-12-04 EP disclosed
US-4634580-A PRE-REDUCTION OF IRON URANIUM PECHINEY (FR) 1987-01-06 US disclosed
US-4136020-A REACTION PRODUCT OF A XANTHOGEN FORMATE AND AN AROMATIC AMINE MINEREC CORPORATION (US) 1979-01-23 US disclosed