Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7011116 | 0.91 | PDCD1 (0.42) | PDCD1CD274MGLL | |
| SCHEMBL20082396 | 0.76 | PDCD1 (0.42) | PDCD1CD274MGLLCXCR4 | |
| Hydrochloric Acid SCHEMBL15006961 | 0.74 | PDCD1 (0.41) | PDCD1CD274CXCR4 | |
| SCHEMBL112848 | 0.74 | PDCD1 (0.44) | PDCD1CD274MGLLCXCR4 | |
| SCHEMBL15882090 | 0.72 | PDCD1 (0.45) | PDCD1CD274MGLLCXCR4 | |
| Hydrochloric Acid SCHEMBL29721354 | 0.71 | PDCD1 (0.44) | PDCD1CD274MGLLCXCR4 | |
| SCHEMBL2752951 | 0.70 | CXCR4 (0.42) | PDCD1CD274MGLLCXCR4 | |
| SCHEMBL3840066 | 0.69 | P2RX7 (0.38) | PDCD1CD274MGLL | |
| SCHEMBL31217456 | 0.69 | PDCD1 (0.34) | PDCD1CD274CXCR4 | |
| Hydrochloric Acid SCHEMBL2339479 | 0.69 | CXCR4 (0.41) | PDCD1CD274CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170369444-A1 | INHIBITORS OF HISTONE DEMETHYLASES | EPITHERAPEUTICS APS (DK) | 2017-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170369444-A1 | INHIBITORS OF HISTONE DEMETHYLASES | KDM1B, KDM3A, KDM1A | PDCD1 1483/4885CD274 2708/4885MGLL 4185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.