Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | TOP1 | P11387 | 9/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5179344 | 0.90 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL12427302 | 0.90 | TOP1 (0.52) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL2199878 | 0.90 | TOP1 (0.52) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL1970509 | 0.88 | KCNH2 (0.47) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL1971640 | 0.83 | KCNH2 (0.46) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL1974491 | 0.81 | STAT3 (0.34) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL1974585 | 0.81 | TOP1 (0.35) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL1975281 | 0.79 | KCNH2 (0.45) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL1972521 | 0.79 | KCNH2 (0.45) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL1973849 | 0.79 | KCNH2 (0.45) | KDM4EALDH1A1HPGDHSD17B10KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1994020-B1 | Substituted quinolones III | AICURIS GMBH & CO KG (DE) | 2011-06-22 | — | — | EP | disclosed |