Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | TOP1 | P11387 | 7/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1973321 | 0.88 | STAT3 (0.40) | STAT3TOP1KDM4EPTGDR2ALDH1A1 | |
| SCHEMBL967928 | 0.87 | KDM4E (0.46) | TOP1KDM4EKCNH2GSK3BALDH1A1 | |
| SCHEMBL1970509 | 0.83 | KCNH2 (0.47) | TOP1KDM4EKCNH2ALDH1A1HPGD | |
| SCHEMBL5118013 | 0.82 | STAT3 (0.33) | STAT3TOP1PTGDR2 | |
| SCHEMBL5179344 | 0.81 | KDM4E (0.48) | TOP1KDM4EKCNH2ALDH1A1HPGD | |
| SCHEMBL1974255 | 0.81 | KDM4E (0.42) | TOP1KDM4EKCNH2ALDH1A1HPGD | |
| SCHEMBL964499 | 0.81 | STAT3 (0.52) | STAT3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL967926 | 0.80 | STAT3 (0.39) | STAT3TOP1KDM4EKCNH2ALDH1A1 | |
| SCHEMBL1971640 | 0.80 | KCNH2 (0.46) | TOP1KDM4EKCNH2ALDH1A1HPGD | |
| SCHEMBL12917115 | 0.79 | KDM4E (0.45) | TOP1KDM4EKCNH2GSK3BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1994020-B1 | Substituted quinolones III | AICURIS GMBH & CO KG (DE) | 2011-06-22 | — | — | EP | disclosed |
| EP-1768973-B1 | SUBSTITUTED QUINOLONES | AICURIS GMBH & CO KG (DE) | 2007-12-05 | — | — | EP | disclosed |