Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 11/20 | 0.92 |
| ▸ | CPB1 | P15086 | 1/20 | 0.62 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19743088 | 1.00 | FOLH1 (0.92) | FOLH1CPB1CPB2HTTMMP2 | |
| SCHEMBL18161459 | 0.96 | FOLH1 (1.00) | FOLH1CPB1CPB2HTTMMP2 | |
| SCHEMBL18145488 | 0.96 | FOLH1 (1.00) | FOLH1CPB1CPB2HTTMMP2 | |
| SCHEMBL19742200 | 0.96 | FOLH1 (1.00) | FOLH1CPB1CPB2HTTMMP2 | |
| SCHEMBL14729484 | 0.96 | FOLH1 (1.00) | FOLH1CPB1CPB2HTTMMP2 | |
| SCHEMBL19743114 | 0.92 | FOLH1 (0.93) | FOLH1CPB1CPB2HTTMMP2 | |
| SCHEMBL19743113 | 0.92 | FOLH1 (0.93) | FOLH1CPB1CPB2HTTMMP2 | |
| SCHEMBL25216970 | 0.90 | FOLH1 (0.78) | FOLH1CPB1CPB2HTTMMP2 | |
| SCHEMBL25195535 | 0.90 | FOLH1 (0.78) | FOLH1CPB1CPB2HTTMMP2 | |
| SCHEMBL29072085 | 0.89 | FOLH1 (0.76) | FOLH1CPB1CPB2HTTMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210137860-A1 | DOUBLE TARGETED CONSTRUCTS TO AFFECT TUMOR KILL | CORNELL UNIVERSITY (US) | 2021-05-13 | — | — | US | disclosed |
| US-10716772-B2 | Double targeted constructs to affect tumor kill | CORNELL UNIVERSITY (US) | 2020-07-21 | — | — | US | disclosed |
| US-20190142770-A1 | DOUBLE TARGETED CONSTRUCTS TO AFFECT TUMOR KILL | CORNELL UNIVERSITY | 2019-05-16 | — | — | US | disclosed |
| US-10179117-B2 | Double targeted constructs to affect tumor kill | CORNELL UNIVERSITY (US) | 2019-01-15 | — | — | US | disclosed |
| US-20170368005-A1 | DOUBLE TARGETED CONSTRUCTS TO AFFECT TUMOR KILL | CORNELL UNIVERSITY | 2017-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210137860-A1 | DOUBLE TARGETED CONSTRUCTS TO AFFECT TUMOR KILL | PSMA2, FOLH1, KLK3 | FOLH1 2/4885CPB1 396/4885CPB2 130/4885 |
| US-10716772-B2 | Double targeted constructs to affect tumor kill | PSMA2, FOLH1, KLK3 | FOLH1 2/4885CPB1 396/4885CPB2 130/4885 |
| US-20170368005-A1 | DOUBLE TARGETED CONSTRUCTS TO AFFECT TUMOR KILL | PSMA2, FOLH1, KLK3 | FOLH1 2/4885CPB1 396/4885CPB2 130/4885 |
| US-20190142770-A1 | DOUBLE TARGETED CONSTRUCTS TO AFFECT TUMOR KILL | PSMA2, FOLH1, KLK3 | FOLH1 2/4885CPB1 396/4885CPB2 130/4885 |
| US-10179117-B2 | Double targeted constructs to affect tumor kill | PSMA2, FOLH1, KLK3 | FOLH1 2/4885CPB1 396/4885CPB2 130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.