SCHEMBL19742200

SCHEMBL19742200

O=C(O)CCC(NC(=O)NC(CCCCNC(=O)OCc1ccccc1)C(=O)O)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 10/20 1.00
CPB1 P15086 1/20 0.66
CPB2 Q96IY4 1/20 0.66
HTT P42858 1/20 0.63
MMP2 P08253 1/20 0.60
MMP9 P14780 1/20 0.60
SIRT2 Q8IXJ6 1/20 0.59
SIRT1 Q96EB6 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18145488 1.00 FOLH1 (1.00) FOLH1CPB1CPB2HTTMMP2
SCHEMBL18161459 1.00 FOLH1 (1.00) FOLH1CPB1CPB2HTTMMP2
SCHEMBL14729484 1.00 FOLH1 (1.00) FOLH1CPB1CPB2HTTMMP2
SCHEMBL19743113 0.97 FOLH1 (0.93) FOLH1CPB1CPB2HTTMMP2
SCHEMBL19743114 0.97 FOLH1 (0.93) FOLH1CPB1CPB2HTTMMP2
SCHEMBL19743085 0.96 FOLH1 (0.92) FOLH1CPB1CPB2HTTMMP2
SCHEMBL19743088 0.96 FOLH1 (0.92) FOLH1CPB1CPB2HTTMMP2
SCHEMBL18145837 0.91 FOLH1 (1.00) FOLH1CPB1CPB2HTTMMP2
SCHEMBL18161580 0.91 FOLH1 (1.00) FOLH1CPB1CPB2HTTMMP2
SCHEMBL22712984 0.91 FOLH1 (1.00) FOLH1CPB1CPB2HTTMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025076128-A1 ADAPTORS FOR ADOPTIVE CELL THERAPY AND COMPOUNDS FOR PREPARING SAME UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2025-04-10 WO disclosed
US-20240425547-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2024-12-26 US disclosed
US-12122851-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2024-10-22 US disclosed
WO-2024116053-A1 PCTA DERIVATIVES, CONJUGATES THEREOF AND USES THEREOF NOVARTIS AG (CH) 2024-06-06 WO disclosed
EP-4249005-A2 18F-LABELED TRIAZOLE CONTAINING PSMA INHIBITORS Cornell University (US) 2023-09-27 EP disclosed
EP-3493856-B1 18F-LABELED TRIAZOLE CONTAINING PSMA INHIBITORS UNIV CORNELL (US) 2023-08-09 EP disclosed
US-20230201383-A1 PSMA TARGETING UREA-BASED LIGANDS FOR PROSTATE CANCER RADIOTHERAPY AND IMAGING RIGSHOSPITALET (DK) 2023-06-29 US disclosed
WO-2023097038-A1 CLEAVABLE RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF FULL-LIFE TECHNOLOGIES U.S. INC. (US) 2023-06-01 WO disclosed
EP-4161585-A1 PSMA TARGETING UREA-BASED LIGANDS FOR PROSTATE CANCER RADIOTHERAPY AND IMAGING University of Copenhagen (DK) 2023-04-12 EP disclosed
US-20220194904-A1 18F-LABELED TRIAZOLE CONTAINING PSMA INHIBITORS CORNELL UNIVERSITY (US) 2022-06-23 US disclosed
US-10894807-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2021-01-19 US disclosed
US-20200377549-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2020-12-03 US disclosed
US-20200377549-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2020-12-03 US disclosed
US-20200317588-A1 18F-LABELED PEPTIDE LIGANDS USEFUL IN PET AND CERENKOV LUMINESCENE IMAGING CORNELL UNIVERSITY (US) 2020-10-08 US disclosed
US-10716772-B2 Double targeted constructs to affect tumor kill CORNELL UNIVERSITY (US) 2020-07-21 US disclosed
US-20190142770-A1 DOUBLE TARGETED CONSTRUCTS TO AFFECT TUMOR KILL CORNELL UNIVERSITY 2019-05-16 US disclosed
US-10179117-B2 Double targeted constructs to affect tumor kill CORNELL UNIVERSITY (US) 2019-01-15 US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 US disclosed
US-20170369454-A1 18F-LABELED TRIAZOLE CONTAINING PSMA INHIBITORS UNIV CORNELL (US) 2017-12-28 US disclosed
US-20170368005-A1 DOUBLE TARGETED CONSTRUCTS TO AFFECT TUMOR KILL CORNELL UNIVERSITY 2017-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240425547-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885CPB1 293/4885CPB2 566/4885
US-10894807-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 FOLH1 1/4885CPB1 293/4885CPB2 566/4885
US-20200317588-A1 18F-LABELED PEPTIDE LIGANDS USEFUL IN PET AND CERENKOV LUMINESCENE IMAGING VIP, CALCA, GLP1R FOLH1 33/4885CPB1 695/4885CPB2 1293/4885
US-20230201383-A1 PSMA TARGETING UREA-BASED LIGANDS FOR PROSTATE CANCER RADIOTHERAPY AND IMAGING KLK3, FOLH1, PSMA7 FOLH1 2/4885CPB1 658/4885CPB2 776/4885
US-10716772-B2 Double targeted constructs to affect tumor kill PSMA2, FOLH1, KLK3 FOLH1 2/4885CPB1 396/4885CPB2 130/4885
US-20170368005-A1 DOUBLE TARGETED CONSTRUCTS TO AFFECT TUMOR KILL PSMA2, FOLH1, KLK3 FOLH1 2/4885CPB1 396/4885CPB2 130/4885
US-20190142770-A1 DOUBLE TARGETED CONSTRUCTS TO AFFECT TUMOR KILL PSMA2, FOLH1, KLK3 FOLH1 2/4885CPB1 396/4885CPB2 130/4885
US-10179117-B2 Double targeted constructs to affect tumor kill PSMA2, FOLH1, KLK3 FOLH1 2/4885CPB1 396/4885CPB2 130/4885
US-20170369454-A1 18F-LABELED TRIAZOLE CONTAINING PSMA INHIBITORS PSMA3, FOLH1, PSMA1 FOLH1 2/4885CPB1 986/4885CPB2 1829/4885
US-20200377549-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885CPB1 293/4885CPB2 566/4885
US-10011632-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 FOLH1 1/4885CPB1 293/4885CPB2 566/4885
US-12122851-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 FOLH1 1/4885CPB1 293/4885CPB2 566/4885
US-20220194904-A1 18F-LABELED TRIAZOLE CONTAINING PSMA INHIBITORS PSMA3, FOLH1, PSMA1 FOLH1 2/4885CPB1 986/4885CPB2 1829/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.