SCHEMBL19743911

SCHEMBL19743911

Nc1cnc(Br)cn1.[LiH]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL40289 0.97
SCHEMBL29729074 0.97
Hydrochloric Acid SCHEMBL30464867 0.94
SCHEMBL21045448 0.84 PIK3CD (0.41)
Formic Acid Methyl Ester SCHEMBL28834546 0.79 ALOX5AP (0.36)
SCHEMBL647114 0.78
SCHEMBL423198 0.78
Hydrochloric Acid SCHEMBL29354497 0.75 HSP90AA1 (0.47)
Cyclopropanecarboxylic Acid Amide SCHEMBL3460472 0.74 CYP3A4 (0.36)
SCHEMBL13606491 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3472154-A1 COMPOUNDS Enterprise Therapeutics Limited (GB) 2019-04-24 EP disclosed
WO-2017221008-A1 COMPOUNDS Enterprise Therapeutics Limited (GB) 2017-12-28 WO disclosed