⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29729074 | 1.00 | — | — | |
| SCHEMBL19743911 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL30464867 | 0.97 | — | — | |
| SCHEMBL21045448 | 0.86 | PIK3CD (0.41) | — | |
| Formic Acid Methyl Ester SCHEMBL28834546 | 0.81 | ALOX5AP (0.36) | — | |
| SCHEMBL423198 | 0.80 | — | — | |
| SCHEMBL647114 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL29354497 | 0.77 | HSP90AA1 (0.47) | — | |
| Cyclopropanecarboxylic Acid Amide SCHEMBL3460472 | 0.77 | CYP3A4 (0.36) | — | |
| SCHEMBL13606491 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2427 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119684334-A | Chemiluminescent probe for targeting Abeta oligomer and preparation method and application thereof | 中国药科大学 | 2025-03-25 | — | — | CN | claimed |
| CN-119281138-A | Core-shell structure porous polymer-carbon nano tube filter membrane and preparation method thereof | 国能神东煤炭集团有限责任公司 | 2025-01-10 | — | — | CN | claimed |
| CN-118084918-A | Chemiluminescent probe, preparation method thereof and application thereof in detection of beta amyloid | 中国药科大学 | 2024-05-28 | — | — | CN | claimed |
| CN-118027070-A | Triazolopyridine bromodomain protein 4 small molecule inhibitor and preparation method and application thereof | 中国药科大学 | 2024-05-14 | — | — | CN | claimed |
| CN-117903069-A | Synthesis method of fampicin intermediate 2-bromo-5-chloropyrazine | 苏州艾缇克药物化学有限公司 | 2024-04-19 | — | — | CN | claimed |
| US-20220402875-A1 | S1P3 Antagonists | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2022-12-22 | — | — | US | claimed |
| EP-3965760-A1 | SYNTHESIS OF CRAC CHANNEL INHIBITORS | Calcimedica, Inc. (US) | 2022-03-16 | — | — | EP | claimed |
| US-20220056053-A1 | SYNTHESIS OF CRAC CHANNEL INHIBITORS | AVENUE CAPITAL MANAGEMENT II, L.P. | 2022-02-24 | — | — | US | claimed |
| CN-114072143-A | Synthesis of CRAC channel inhibitors | 钙医学公司 | 2022-02-18 | — | — | CN | claimed |
| WO-2020227312-A1 | SYNTHESIS OF CRAC CHANNEL INHIBITORS | CALCIMEDICA, INC. (US) | 2020-11-12 | — | — | WO | claimed |
| US-20160297762-A1 | S1P3 ANTAGONISTS | TEVA PHARMACEUTICAL INDUSTRIES LIMITED (IL) | 2016-10-13 | — | — | US | claimed |
| WO-2015082357-A1 | S1P3 ANTAGONISTS | SIENA BIOTECH S.P.A. (IT) | 2015-06-11 | — | — | WO | claimed |
| EP-2878339-A1 | SIP3 antagonists | Siena Biotech S.p.A. (IT) | 2015-06-03 | — | — | EP | claimed |
| EP-1654260-A4 | 6-MENBERED HETEROARYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | PFIZER PROD INC (US) | 2008-09-24 | — | — | EP | claimed |
| EP-1654260-A2 | 6-MENBERED HETEROARYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | Pfizer Products Inc. (US) | 2006-05-10 | — | — | EP | claimed |
| US-20050107381-A1 | 6-membered heteroaryl compounds for the treatment of neurodegenerative disorders | PFIZER, INC. | 2005-05-19 | — | — | US | claimed |
| WO-2005011601-A2 | 6-MENBERED HETEROARYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | PFIZER PRODUCTS, INC. (US) | 2005-02-10 | — | — | WO | claimed |
| US-20040034225-A1 | Aryl-substituted n, n-heterocyclic compounds, method for their preparationand their use in therapeutics and diagnostics | UNIVERSITY CATHOLIQUE DE LOUVAIN (BE) | 2004-02-19 | — | — | US | claimed |
| EP-1292580-A1 | PYRAZINE AND IMIDAZOPYRAZINE DERIVATIVES AS ANTIOXIDANTS | UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2003-03-19 | — | — | EP | claimed |
| WO-2001087853-A1 | ARYL-SUBSTITUTED N,N-HETEROCYCLIC COMPOUNDS, METHOD FOR THEIR PREPARATION AND THEIR USE IN THERAPEUTICS AND DIAGNOSTICS | UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2001-11-22 | — | — | WO | claimed |