Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.54 |
| ▸ | ANPEP | P15144 | 2/20 | 0.54 |
| ▸ | DPP7 | Q9UHL4 | 9/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.38 |
| ▸ | DPP4 | P27487 | 5/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21682451 | 1.00 | MMP2 (0.54) | MMP2ANPEPDPP7DPP8DPP9 | |
| SCHEMBL18339420 | 1.00 | MMP2 (0.54) | MMP2ANPEPDPP7DPP8DPP9 | |
| SCHEMBL19744398 | 1.00 | MMP2 (0.54) | MMP2ANPEPDPP7DPP8DPP9 | |
| SCHEMBL29260191 | 1.00 | MMP2 (0.54) | MMP2ANPEPDPP7DPP8DPP9 | |
| SCHEMBL16171925 | 0.87 | MMP2 (0.71) | MMP2ANPEPDPP7DPP8DPP9 | |
| SCHEMBL28539537 | 0.85 | MMP2 (0.42) | MMP2ANPEPDPP7DPP8DPP9 | |
| SCHEMBL29162169 | 0.85 | MMP2 (0.42) | MMP2ANPEPDPP7DPP8DPP9 | |
| SCHEMBL25368206 | 0.83 | MMP2 (0.41) | MMP2ANPEPDPP7DPP8DPP9 | |
| SCHEMBL29930727 | 0.83 | MMP2 (0.41) | MMP2ANPEPDPP7DPP8DPP9 | |
| SCHEMBL29930529 | 0.83 | MMP2 (0.41) | MMP2ANPEPDPP7DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076607-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2024-05-24 | — | — | CN | disclosed |
| EP-3472149-A1 | HETEROCYCLIC PROLINAMIDE DERIVATIVES | ORION OPTHALMOLOGY LLC (US) | 2019-04-24 | — | — | EP | disclosed |
| WO-2017222915-A1 | HETEROCYCLIC PROLINAMIDE DERIVATIVES | INCEPTION 4, INC. (US) | 2017-12-28 | — | — | WO | disclosed |