Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 17/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19747650 | 0.94 | NR1H2 (0.45) | NR1H2PTGS2NR1H3 | |
| SCHEMBL21196724 | 0.93 | NR1H2 (0.52) | NR1H2NR1H3 | |
| SCHEMBL23922712 | 0.92 | NR1H2 (0.45) | NR1H2PTGS2NR1H3 | |
| SCHEMBL21214132 | 0.87 | NR1H2 (0.51) | NR1H2NR1H3 | |
| SCHEMBL21196617 | 0.87 | NR1H2 (0.51) | NR1H2NR1H3 | |
| SCHEMBL19744464 | 0.82 | NR1H2 (0.46) | NR1H2NR1H3 | |
| SCHEMBL23936708 | 0.81 | PTGS2 (0.60) | PTGS2DRD2 | |
| SCHEMBL21196535 | 0.80 | NR1H2 (0.51) | NR1H2NR1H3DRD2 | |
| SCHEMBL19744490 | 0.75 | NR1H2 (0.52) | NR1H2NR1H3 | |
| SCHEMBL19745891 | 0.75 | NR1H2 (0.55) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3475277-A1 | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | Bioimics AB (SE) | 2019-05-01 | — | — | EP | disclosed |
| WO-2017222466-A1 | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | BIOIMICS AB (SE) | 2017-12-28 | — | — | WO | disclosed |