Flavanone

Flavanone

SCHEMBL19745

O=C1CC(c2ccccc2)Oc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAOB P27338 12/20 1.00
AR P10275 4/20 1.00
ADORA3 P0DMS8 3/20 1.00
CYP19A1 P11511 3/20 1.00
KDM4E B2RXH2 1/20 1.00
HSD17B10 Q99714 1/20 1.00
NPC1 O15118 3/20 0.79
RAB9A P51151 3/20 0.79
MAPT P10636 2/20 0.79
CYP3A4 P08684 1/20 0.79
MAPK1 P28482 1/20 0.79
MAOA P21397 1/20 0.67
PSMB5 P28074 1/20 0.67
HSD11B1 P28845 1/20 0.64
AKR1C3 P42330 1/20 0.64
ABCB1 P08183 1/20 0.61
ABCG2 Q9UNQ0 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flavanone SCHEMBL29470801 1.00 MAOB (1.00) MAOBARADORA3CYP19A1KDM4E
Flavanone SCHEMBL12660199 1.00 MAOB (1.00) MAOBARADORA3CYP19A1KDM4E
Flavanone SCHEMBL29843289 1.00 MAOB (1.00) MAOBARADORA3CYP19A1KDM4E
Flavanone SCHEMBL12189591 1.00 MAOB (1.00) MAOBARADORA3CYP19A1KDM4E
Flavanone SCHEMBL22715765 0.98 MAOB (0.96) MAOBARADORA3CYP19A1KDM4E
Flavanone SCHEMBL11733114 0.98 MAOB (0.96) MAOBARADORA3CYP19A1KDM4E
Flavanone SCHEMBL11666711 0.92 MAOB (0.84) MAOBARADORA3CYP19A1KDM4E
Flavanone SCHEMBL28795677 0.91 MAOB (0.82) MAOBARADORA3CYP19A1KDM4E
Flavanone SCHEMBL31187243 0.90 MAOB (0.81) MAOBARADORA3CYP19A1KDM4E
SCHEMBL12660200 0.89 MAOB (0.79) MAOBARADORA3CYP19A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 12352 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748368-A1 COMPOSITION FOR ORAL HYGIENE PRODUCTS COMPRISING N-CETYLPYRIDINIUM CHLORIDE, A FLAVONOID AND A POLYMER Curaden AG (CH) 2026-05-27 EP claimed
CN-122080007-A Flavanone indole derivative and preparation method and application thereof 2026-05-26 CN claimed
CN-122071729-A Chiral dihydroflavone Process for the preparation of compounds 北京化工大学 2026-05-22 CN claimed
CN-122071447-A Dihydro flavone Process for the preparation of compounds 北京化工大学 2026-05-22 CN claimed
CN-122059625-A Mineral wool binder 洛科威有限公司 2026-05-19 CN claimed
CN-122056926-A Probiotic composition containing melatonin and application of composition in sleep 南京北极光生物科技有限公司 2026-05-19 CN claimed
WO-2026099917-A1 METHOD FOR PRODUCING USEFUL SUBSTANCE, CULTURE SOLUTION FOR CULTURING ALGAE, AND DEVICE FOR PRODUCING USEFUL SUBSTANCE NTT株式会社 2026-05-15 WO claimed
CN-122036756-A Flavanone thiazole derivative and preparation method and application thereof 南通大学 2026-05-15 CN claimed
WO-2026100273-A1 METHOD FOR PRODUCING USEFUL SUBSTANCE, CULTURE SOLUTION FOR CULTURING ALGAE, APPARATUS FOR PRODUCING USEFUL SUBSTANCE, AND ALGAE CONTAINING USEFUL SUBSTANCE NTT株式会社 2026-05-15 WO claimed
EP-4719376-A2 ANTIPERSPIRANT COMPOSITIONS Elementis Specialties, Inc. (US) 2026-04-08 EP claimed
EP-0223245-A2 Curable compositions for dental drugs having sustained release property MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1987-05-27 EP claimed
CN-85105079-A The preparation of flavanone derivative 1987-01-28 CN claimed
EP-0052086-B1 PROCESS FOR PRODUCING FLAVONE DERIVATIVES WITH MEDICINAL ACTIVITY BONOMELLI S.p.A. (IT) 1986-01-29 EP claimed
EP-0052086-A1 Process for producing flavone derivatives with medicinal activity BONOMELLI S.p.A. (IT) 1982-05-19 EP claimed
US-4290957-A SWEETENERS DYNAPOL (US) 1981-09-22 US claimed
US-4214963-A Process for the preparation of substituted 4H-pyran-4-ones Garcia de Lama, Javier (ES) 1980-07-29 US claimed
US-4105675-A REDUCING ACYLATED FLAVANONE WITH ALKALI BOROHYDRIDE TO REMOVE OXYGEN FUNCTION AT 4-POSITION; OXIDIZING WITH HALOGENATED BENZOQUINONE TO FORM SALT THE COCA-COLA COMPANY (US) 1978-08-08 US claimed
US-4025535-A Sulfoalkylated flavanone sweeteners DYNAPOL CORPORATION (US) 1977-05-24 US claimed
US-4013801-A EDIBLES SWEETENED WITH FLAVANONES DYNAPOL CORPORATION (US) 1977-03-22 US claimed
US-3953423-A Preparation of a new flavanone derivative H. TROMMSDORFF (DT) 1976-04-27 US claimed