Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.82 |
| ▸ | AR | P10275 | 4/20 | 0.82 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.82 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.82 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.82 |
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flavanone SCHEMBL29470801 | 0.91 | MAOB (1.00) | MAOBARADORA3CYP19A1KDM4E | |
| Flavanone SCHEMBL29843289 | 0.91 | MAOB (1.00) | MAOBARADORA3CYP19A1KDM4E | |
| Flavanone SCHEMBL12189591 | 0.91 | MAOB (1.00) | MAOBARADORA3CYP19A1KDM4E | |
| Flavanone SCHEMBL19745 | 0.91 | MAOB (1.00) | MAOBARADORA3CYP19A1KDM4E | |
| Flavanone SCHEMBL12660199 | 0.91 | MAOB (1.00) | MAOBARADORA3CYP19A1KDM4E | |
| Flavanone SCHEMBL22715765 | 0.89 | MAOB (0.96) | MAOBARADORA3CYP19A1KDM4E | |
| Flavanone SCHEMBL11733114 | 0.89 | MAOB (0.96) | MAOBARADORA3CYP19A1KDM4E | |
| SCHEMBL30498925 | 0.87 | AR (0.64) | MAOBARADORA3CYP19A1KDM4E | |
| Flavanone SCHEMBL4965453 | 0.86 | MAOB (0.64) | MAOBARADORA3CYP19A1KDM4E | |
| Flavanone SCHEMBL4965454 | 0.86 | MAOB (0.64) | MAOBARADORA3CYP19A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114763359-A | Stilbene flavanone type compound, preparation method and pharmaceutical application thereof | 复旦大学 | 2022-07-19 | — | — | CN | claimed |
| CN-114763359-A | Stilbene flavanone type compound, preparation method and pharmaceutical application thereof | 复旦大学 | 2022-07-19 | — | — | CN | disclosed |
| CN-114763359-A | Stilbene flavanone type compound, preparation method and pharmaceutical application thereof | 复旦大学 | 2022-07-19 | — | — | CN | disclosed |
| CN-114763359-A | Stilbene flavanone type compound, preparation method and pharmaceutical application thereof | 复旦大学 | 2022-07-19 | — | — | CN | disclosed |