Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2693566 | 0.79 | — | — | |
| SCHEMBL4929033 | 0.76 | CYP2C19 (0.40) | CYP2C19 | |
| SCHEMBL6860579 | 0.76 | CYP2C19 (0.45) | CYP2C19 | |
| SCHEMBL4689732 | 0.74 | CYP2C19 (0.48) | CYP2C19 | |
| SCHEMBL16150052 | 0.74 | CYP2C19 (0.48) | CYP2C19 | |
| SCHEMBL19746316 | 0.74 | GAA (0.38) | — | |
| SCHEMBL4689889 | 0.71 | CYP2C19 (0.32) | CYP2C19 | |
| SCHEMBL3079293 | 0.71 | PTGS1 (0.31) | — | |
| SCHEMBL19746775 | 0.70 | — | — | |
| SCHEMBL7053868 | 0.61 | ALOX15 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017223349-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. (US) | 2017-12-28 | — | — | WO | disclosed |