Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
| ▸ | SDHB | P21912 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LPO | P22079 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19747008 | 0.89 | HDAC6 (0.50) | HDAC6HDAC1HDAC8HDAC5SDHB | |
| SCHEMBL19746691 | 0.86 | HDAC6 (0.56) | HDAC6HDAC1HDAC8ADORA2A | |
| SCHEMBL19746625 | 0.85 | HDAC6 (0.60) | HDAC6HDAC1HDAC8ADORA2AHDAC5 | |
| SCHEMBL19747484 | 0.84 | HDAC6 (0.56) | HDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL19747037 | 0.83 | HDAC6 (0.46) | HDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL19746010 | 0.82 | HDAC6 (0.49) | HDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL19746690 | 0.82 | HDAC6 (0.44) | HDAC6HDAC1HDAC8 | |
| SCHEMBL19746424 | 0.81 | HDAC6 (0.50) | HDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL19746136 | 0.81 | HDAC6 (0.57) | HDAC6HDAC1HDAC8ADORA2AHDAC5 | |
| SCHEMBL19746278 | 0.79 | HDAC6 (0.49) | HDAC6HDAC1HDAC8HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017222952-A1 | 3- HETEROARYL SUBSTITUTED 5-TRIFLUOROMETHYL OXADIAZOLES AS HISTONE DEACETYLASE 6 (HDAC6) INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2017-12-28 | — | — | WO | claimed |
| US-11708358-B2 | Fungicidal oxadiazoles | FMC CORPORATION (US) | 2023-07-25 | — | — | US | disclosed |
| US-11708358-B2 | Fungicidal oxadiazoles | FMC CORPORATION (US) | 2023-07-25 | — | — | US | disclosed |
| WO-2022133114-A1 | FUNGICIDAL OXADIAZOLES AND THEIR MIXTURES | FMC CORPORATION (US) | 2022-06-23 | — | — | WO | disclosed |
| US-20200148672-A1 | FUNGICIDAL OXADIAZOLES | FMC CORPORATION | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200148672-A1 | FUNGICIDAL OXADIAZOLES | OXA1L, NOX1, TH | HDAC6 1038/4885HDAC1 1586/4885HDAC8 2957/4885 |
| US-11708358-B2 | Fungicidal oxadiazoles | OXA1L, NOX1, TH | HDAC6 1038/4885HDAC1 1586/4885HDAC8 2957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.