Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 19/20 | 0.59 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19748784 | 0.91 | FOLH1 (0.59) | FOLH1ITGB3ITGA2B | |
| SCHEMBL19748823 | 0.90 | FOLH1 (0.61) | FOLH1 | |
| SCHEMBL19748291 | 0.87 | FOLH1 (0.69) | FOLH1 | |
| SCHEMBL19754087 | 0.84 | FOLH1 (0.67) | FOLH1 | |
| SCHEMBL19743111 | 0.82 | FOLH1 (0.72) | FOLH1 | |
| SCHEMBL19743110 | 0.82 | FOLH1 (0.72) | FOLH1 | |
| SCHEMBL11977608 | 0.80 | FOLH1 (0.84) | FOLH1 | |
| SCHEMBL13559320 | 0.79 | FOLH1 (0.72) | FOLH1 | |
| SCHEMBL23077794 | 0.79 | FOLH1 (0.82) | FOLH1 | |
| SCHEMBL11977609 | 0.78 | FOLH1 (0.84) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3474903-A1 | DOUBLE TARGETED CONSTRUCTS TO AFFECT TUMOR KILL | Cornell University (US) | 2019-05-01 | — | — | EP | disclosed |
| WO-2017223357-A1 | DOUBLE TARGETED CONSTRUCTS TO AFFECT TUMOR KILL | CORNELL UNIVERSITY (US) | 2017-12-28 | — | — | WO | disclosed |