Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 17/20 | 0.67 |
| ▸ | ALB | P02768 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19754090 | 0.89 | ATM (0.53) | FOLH1ALBATM | |
| SCHEMBL19743111 | 0.89 | FOLH1 (0.72) | FOLH1ALB | |
| SCHEMBL19743110 | 0.89 | FOLH1 (0.72) | FOLH1ALB | |
| SCHEMBL19748291 | 0.88 | FOLH1 (0.69) | FOLH1ALB | |
| SCHEMBL19748432 | 0.84 | FOLH1 (0.59) | FOLH1 | |
| SCHEMBL19748972 | 0.80 | FOLH1 (0.68) | FOLH1ALB | |
| SCHEMBL22247625 | 0.80 | FOLH1 (0.62) | FOLH1ALB | |
| SCHEMBL19747822 | 0.79 | FOLH1 (0.70) | FOLH1ALB | |
| SCHEMBL9903622 | 0.79 | FOLH1 (0.74) | FOLH1 | |
| SCHEMBL2475977 | 0.79 | FOLH1 (0.74) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170368005-A1 | DOUBLE TARGETED CONSTRUCTS TO AFFECT TUMOR KILL | CORNELL UNIVERSITY | 2017-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170368005-A1 | DOUBLE TARGETED CONSTRUCTS TO AFFECT TUMOR KILL | PSMA2, FOLH1, KLK3 | FOLH1 2/4885ALB 1812/4885ATM 2203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.