Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL782671 | 1.00 | NAE1 (0.32) | NAE1UBA3 | |
| SCHEMBL23455993 | 0.91 | NAE1 (0.31) | NAE1UBA3 | |
| SCHEMBL19749333 | 0.88 | NAE1 (0.32) | NAE1UBA3 | |
| SCHEMBL14719818 | 0.88 | NAE1 (0.32) | NAE1UBA3 | |
| SCHEMBL14719817 | 0.88 | NAE1 (0.32) | NAE1UBA3 | |
| SCHEMBL783683 | 0.83 | NAE1 (0.49) | NAE1UBA3 | |
| SCHEMBL782570 | 0.82 | OPRM1 (0.31) | — | |
| SCHEMBL22907437 | 0.81 | — | — | |
| SCHEMBL782645 | 0.81 | — | — | |
| SCHEMBL782794 | 0.81 | NAE1 (0.51) | NAE1UBA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3323414-A1 | INHIBITORS OF NEDD8-ACTIVATING ENZYME | Millennium Pharmaceuticals, Inc. (US) | 2018-05-23 | — | — | EP | disclosed |
| US-9850214-B2 | Inhibitors of NEDD8-activating enzyme | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-12-26 | — | — | US | disclosed |