Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1974982 | 1.00 | ALDH1A1 (0.51) | ALDH1A1KDM4ELMNAGAACYP19A1 | |
| SCHEMBL12555929 | 0.90 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNAGAAHSD17B10 | |
| SCHEMBL4259143 | 0.85 | ALDH1A1 (0.64) | ALDH1A1KDM4ELMNAGAAHSD17B10 | |
| SCHEMBL4259141 | 0.85 | ALDH1A1 (0.64) | ALDH1A1KDM4ELMNAGAAHSD17B10 | |
| Rizedisben SCHEMBL12555821 | 0.83 | CYP19A1 (0.46) | ALDH1A1KDM4ELMNAGAACYP19A1 | |
| Rizedisben SCHEMBL1972916 | 0.82 | CYP19A1 (0.45) | ALDH1A1KDM4ELMNAGAACYP19A1 | |
| SCHEMBL4265463 | 0.81 | KDM4E (0.54) | ALDH1A1KDM4ELMNAGAACYP19A1 | |
| SCHEMBL15483213 | 0.81 | ALDH1A1 (0.49) | ALDH1A1KDM4ELMNAGAAMAPT | |
| SCHEMBL1986772 | 0.80 | CYP2C9 (0.53) | ALDH1A1KDM4EGAAUSP2MAPT | |
| SCHEMBL2637738 | 0.79 | CYP19A1 (0.62) | CYP19A1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8658129-B2 | Agents and methods for the imaging of myelin basic protein | GENERAL ELECTRIC COMPANY (US) | 2014-02-25 | — | — | US | disclosed |
| US-20110142759-A1 | AGENTS AND METHODS FOR THE IMAGING OF MYELIN BASIC PROTEIN | GENERAL ELECTRIC COMPANY (US) | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110142759-A1 | AGENTS AND METHODS FOR THE IMAGING OF MYELIN BASIC PROTEIN | MAG, PMP22, MYT1 | ALDH1A1 4733/4885KDM4E 3161/4885LMNA 472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.