⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21064227 | 1.00 | — | — | |
| SCHEMBL20200119 | 0.75 | — | — | |
| SCHEMBL8345081 | 0.75 | — | — | |
| SCHEMBL19116254 | 0.74 | — | — | |
| SCHEMBL19941871 | 0.74 | — | — | |
| SCHEMBL23280514 | 0.74 | — | — | |
| SCHEMBL23221169 | 0.71 | — | — | |
| SCHEMBL22876807 | 0.71 | PIK3CD (0.32) | — | |
| SCHEMBL21728703 | 0.71 | L3MBTL1 (0.36) | — | |
| SCHEMBL84339 | 0.71 | KMT2A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230372520-A1 | ANTI-MUC1 ANTIBODY-DRUG CONJUGATE | DAIICHI SANKYO CO., LTD. (JP) | 2023-11-23 | — | — | US | disclosed |
| WO-2022115451-A1 | MCL-1 INHIBITOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE | NOVARTIS AG (CH) | 2022-06-02 | — | — | WO | disclosed |
| WO-2021030665-A1 | FORMULATIONS OF BENZAZEPINE CONJUGATES AND USES THEREOF | SILVERBACK THERAPEUTICS, INC. (US) | 2021-02-18 | — | — | WO | disclosed |
| US-10906974-B2 | Anti-GPR20 antibody and anti-GPR20 antibody-drug conjugate | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-02-02 | — | — | US | disclosed |
| EP-3129063-B1 | ANTI-HER3 ANTIBODY-DRUG CONJUGATE | DAIICHI SANKYO CO LTD (JP) | 2021-01-27 | — | — | EP | disclosed |
| WO-2020236825-A2 | MCL-1 INHIBITOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE | NOVARTIS AG (CH) | 2020-11-26 | — | — | WO | disclosed |
| US-20190094246-A1 | DETECTION OF NEURODEGENERATIVE DISEASES | AMONETA DIAGNOSTICS SAS (FR) | 2019-03-28 | — | — | US | disclosed |
| US-9872924-B2 | Antibody-drug conjugate produced by binding through linker having hydrophilic structure | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2018-01-23 | — | — | US | disclosed |
| US-9850312-B2 | Anti-TROP2 antibody-drug conjugate | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-12-26 | — | — | US | disclosed |