Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18593709 | 0.87 | MAPK14 (0.49) | ALDH1A1MAPTKMT2AMEN1ATM | |
| SCHEMBL19750004 | 0.86 | MAPK13 (0.53) | ALDH1A1MAPTKMT2AGFERNTRK1 | |
| SCHEMBL17449180 | 0.86 | MAPK13 (0.58) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL19102034 | 0.79 | RAF1 (0.41) | ALDH1A1KMT2AMEN1ATML3MBTL1 | |
| SCHEMBL13860934 | 0.77 | NTRK1 (0.70) | ALDH1A1MAPTKMT2AMEN1ATM | |
| SCHEMBL1011730 | 0.75 | MAPK14 (0.65) | ALDH1A1KMT2AMEN1ATML3MBTL1 | |
| SCHEMBL4463042 | 0.74 | KMT2A (0.65) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL1012616 | 0.74 | MAPK13 (0.66) | MAPK13MAPK12MAPK11MAPK14GAA | |
| SCHEMBL1015652 | 0.74 | ALDH1A1 (0.54) | ALDH1A1KMT2AATML3MBTL1NTRK1 | |
| SCHEMBL15490413 | 0.74 | KCNJ6 (0.65) | ALDH1A1MAPTKMT2AMEN1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10301288-B2 | Kinase inhibitors | TOPIVERT PHARMA LIMITED (GB) | 2019-05-28 | — | — | US | disclosed |
| US-20180086741-A1 | KINASE INHIBITORS | OXULAR ACQUISITIONS LIMITED (GB) | 2018-03-29 | — | — | US | disclosed |
| US-9850233-B2 | Kinase inhibitors | RESPIVERT LIMITED (GB) | 2017-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086741-A1 | KINASE INHIBITORS | SYK, BTK, SRC | ALDH1A1 4104/4885MAPT 4154/4885KMT2A 1650/4885 |
| US-10301288-B2 | Kinase inhibitors | SYK, BTK, SRC | ALDH1A1 4104/4885MAPT 4154/4885KMT2A 1650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.