Androsterone

Androsterone

SCHEMBL19750468

C[C@]12CCC3[C@@H](CC[C@@H]4C[C@H](O)CC[C@]34C)C1CCC2=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
G6PD P11413 5/20 1.00
GPBAR1 Q8TDU6 4/20 1.00
LMNA P02545 3/20 1.00
CYP3A4 P08684 3/20 1.00
MEN1 O00255 3/20 1.00
KMT2A Q03164 3/20 1.00
SHBG P04278 2/20 1.00
SERPINA6 P08185 2/20 1.00
MAPK1 P28482 2/20 1.00
HSD17B3 P37058 1/20 1.00
PMP22 Q01453 1/20 1.00
AKR1B10 O60218 1/20 1.00
AKR1B1 P15121 1/20 1.00
CYP2D6 P10635 1/20 1.00
TSHR P16473 1/20 1.00
NFKB1 P19838 1/20 1.00
CYP2C19 P33261 1/20 1.00
ALDH1A1 P00352 1/20 0.67
TP53 P04637 1/20 0.67
MAPT P10636 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Androsterone SCHEMBL10273502 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL269982 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL13175783 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Epiandrosterone SCHEMBL295167 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL12811704 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL15426610 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL23031469 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL9940929 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL21114416 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL15963588 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3296405-B1 METHOD AND KIT FOR SUPER-HIGH-SENSITIVITY MEASUREMENT OF PROTEIN AND NUCLEIC ACID, AND NOVEL ENZYME SUBSTRATE ITO ETSURO (JP) 2019-10-09 EP disclosed
EP-3296405-A1 METHOD AND KIT FOR SUPER-HIGH-SENSITIVITY MEASUREMENT OF PROTEIN AND NUCLEIC ACID, AND NOVEL ENZYME SUBSTRATE Ito, Etsuro (JP) 2018-03-21 EP disclosed
US-9851309-B2 Ultra-high-sensitive assay of protein and nucleic acid and kit, and novel enzyme substrate Watabe, Satoshi (JP) 2017-12-26 US disclosed