Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15099972 | 0.81 | KMT2A (0.37) | KMT2ANR1I2KDM4EHTT | |
| SCHEMBL14845738 | 0.80 | NR1I2 (0.39) | KMT2ANR1I2KDM4EHTT | |
| SCHEMBL1466715 | 0.80 | KDM4E (0.46) | KMT2ANR1I2KDM4EHTT | |
| SCHEMBL19085813 | 0.78 | KDM4E (0.33) | KMT2AKDM4EHTTCFTR | |
| SCHEMBL23278435 | 0.74 | MAPT (0.38) | KDM4ECFTR | |
| SCHEMBL12745350 | 0.73 | NR1I2 (0.38) | CNR2KMT2ANR1I2KDM4EHTT | |
| SCHEMBL14403617 | 0.65 | MAPT (0.46) | KMT2A | |
| SCHEMBL15099967 | 0.60 | CFTR (0.35) | KMT2ANR1I2KDM4EHTTCFTR | |
| SCHEMBL13222643 | 0.60 | PRKCI (0.53) | KMT2AKDM4E | |
| SCHEMBL12827234 | 0.59 | CFTR (0.36) | NR1I2CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3091011-B1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMA (US) | 2017-12-27 | — | — | EP | disclosed |