Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | F2R | P25116 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1465623 | 0.87 | MAPT (0.49) | MAPTPOLBATMCCR2CYP19A1 | |
| SCHEMBL19077832 | 0.86 | MAPT (0.45) | MAPTPOLBATMCCR2CYP19A1 | |
| SCHEMBL1465256 | 0.86 | LMNA (0.43) | MAPTPOLBATMMEN1LMNA | |
| SCHEMBL8124685 | 0.77 | CCR2 (0.62) | MAPTPOLBATMCCR2CYP19A1 | |
| SCHEMBL8131716 | 0.74 | MAPT (0.50) | MAPTPOLBATMCCR2CYP19A1 | |
| SCHEMBL26597106 | 0.73 | POLB (0.52) | MAPTPOLBATMCCR2CYP19A1 | |
| SCHEMBL1252366 | 0.73 | CCR2 (0.51) | MAPTPOLBATMCCR2CYP19A1 | |
| SCHEMBL2122743 | 0.72 | CYP19A1 (0.66) | MAPTPOLBATMCCR2CYP19A1 | |
| SCHEMBL19335128 | 0.71 | CYP19A1 (0.53) | MAPTCYP19A1MEN1LMNAKMT2A | |
| SCHEMBL2001099 | 0.70 | CYP19A1 (0.46) | MAPTPOLBCCR2CYP19A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835020-B2 | Blue fluorescent composition and organic electroluminescent device using the same | LG DISPLAY CO., LTD. (KR) | 2014-09-16 | — | — | US | disclosed |
| WO-2007117715-A2 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2007-10-18 | — | — | WO | disclosed |